Can I get it?
Yes, if a doctor decides it is right for you. Compounded rosacea spot formula is prepared to prescription by a compounding pharmacy after a medical review; allow a few days for it to be made.
Compounded rosacea spot formula · BurgasPrescription only
Online medical consultation for Compounded rosacea spot formula in Burgas.
An EU-licensed doctor reviews your case and, if eligible, issues an electronic prescription valid in any pharmacy in Bulgaria. Consultation €35, refunded if the doctor decides it is not safe to prescribe.
- Prepared to prescription by a compounding pharmacy
- Ivermectin and metronidazole, both EU-authorised rosacea actives
- 3-month course with review
Start consultationStart consultation · €35
Full refund if a review is not approved · Medication, if prescribed, is dispensed and paid for separately at a pharmacy.
IN PLAIN TERMS
What Compounded rosacea spot formula is, and how to get treatment
Compounded rosacea spot formula is used in weight management. Whether it suits you depends on your medical history, your other medicines and your goals — which is exactly what a consultation is for.
Compounded rosacea spot formula is a magistral preparation: its components are authorised medicines in the EU, and a compounding pharmacy combines them to a licensed doctor's prescription. The combination itself is not a licensed product.
What can I take instead?
Our doctors review every Dermatology option and recommend what fits your history and goals.
See all Dermatology optionsWhat do the studies show?
Every trial behind Compounded rosacea spot formula is listed below with its registry number, how many people took part, and whether the results are peer-reviewed or a company announcement.
Jump to the studiesLocal consultation facts
Can I get Compounded rosacea spot formula in Burgas?
Yes. People in Burgas, Bulgaria, can request an online doctor consultation about Compounded rosacea spot formula with Hi-Doctor. A licensed EU doctor reviews the case and issues a prescription only when clinically appropriate. If approved, the EU prescription arrives as a PDF for a pharmacist in Bulgaria, who dispenses the locally marketed equivalent containing Rosacea-papulopustular-formula.
Availability
Compounded rosacea spot formula is available to residents of Bulgaria through the online consultation. A prescription follows only if the doctor approves it.
- Country
- Bulgaria
- Language of service
- Spanish and English
- Prescription turnaround
- In less than 4 hours on average, only if the doctor approves
- Honoured locally
- PDF honoured locally for an equivalent containing Rosacea-papulopustular-formula
How the EU prescription works where you are: In Bulgaria, show the approved prescription PDF to a pharmacist. They honour it under EU cross-border rules and dispense the locally marketed equivalent containing Rosacea-papulopustular-formula.
VERIFIED EVIDENCE
Compounded rosacea spot formula: evidence and regulatory guide.
WHAT IT IS
How it works
A compounded gel combining ivermectin, which acts on Demodex mites and inflammation, with metronidazole and barrier-supporting niacinamide.
DEVELOPMENT STAGE
Pharmacy-compounded preparation
Trial register2 registered trials
Every NCT identifier links to its ClinicalTrials.gov record. A readout is not the same as peer-reviewed publication.
| TRIAL / NCT | POPULATION | PARTICIPANTS | STATUS | READOUT / COMPLETION |
|---|---|---|---|---|
| Stein Gold 2014 (two pivotal studies, ivermectin 1% cream vs vehicle) | Adults with moderate to severe papulopustular rosacea, once daily for 12 weeks (683 and 688 enrolled) | 1,371 | Read out | 2014 |
| ATTRACT (Taieb 2015, ivermectin 1% cream vs metronidazole 0.75% cream)NCT01493947 | Adults with moderate to severe papulopustular rosacea, 16 weeks, investigator-blinded | — | Read out | 2015 |
What the studies reported
Results are grouped by source and evidence grade so journal data and manufacturer announcements cannot be confused.
Peer-reviewed
Stein Gold L et al. J Drugs Dermatol 2014;13(3):316-323| DOSE OR GROUP | MEAN WEIGHT CHANGE | WEEKS |
|---|---|---|
| Ivermectin 1% cream, once daily (study 1) | 38.4% clear or almost clear; 76.0% fewer inflammatory lesions | 12 |
| Vehicle (study 1) | 11.6% clear or almost clear; 50.0% fewer lesions | 12 |
| Ivermectin 1% cream, once daily (study 2) | 40.1% clear or almost clear; 75.0% fewer inflammatory lesions | 12 |
| Vehicle (study 2) | 18.8% clear or almost clear; 50.0% fewer lesions | 12 |
These results are for the licensed ivermectin 1% cream alone. The compounded combination with metronidazole and niacinamide has not been studied as a product; the doctor weighs the component evidence when prescribing.
Peer-reviewed
Taieb A et al. Br J Dermatol 2015;172(4):1103-1110 (ATTRACT)| DOSE OR GROUP | MEAN WEIGHT CHANGE | WEEKS |
|---|---|---|
| Ivermectin 1% cream, once daily | Greater reduction in inflammatory lesions than metronidazole 0.75% twice daily | 16 |
Investigator-blinded rather than double-blind. In the 36-week extension, relapse after stopping came later with ivermectin (median 115 vs 85 days).
NAMED SAFETY SIGNALS
What has been reported with Compounded rosacea spot formula.
Application-site burning, itching and dryness
The most frequent effects of both ivermectin and metronidazole in trials, usually mild; fewer dermatological adverse events were reported with ivermectin than vehicle in the pivotal studies.
Compounded product
Prepared to prescription by a pharmacy under national magistral rules; stability and shelf life follow the pharmacy's label rather than an EU marketing authorisation.
FormCompounded gel
FrequencyOnce a day
ResultsFrom week 4, judged at 12 weeks
StatusPrescription only
About
What is Compounded rosacea spot formula?
Active ingredient: Rosacea-papulopustular-formula · Dosages: Ivermectin 1% + metronidazole 0.75% + niacinamide 2%
The spot formula is a magistral preparation combining ivermectin 1%, metronidazole 0.75% and niacinamide 2% in one gel, made by a compounding pharmacy after the prescription is issued. Ivermectin 1% cream and metronidazole 0.75% are each authorised in the EU for the papules and pustules of rosacea.
In the pivotal 12-week trials of ivermectin 1% cream alone, inflammatory lesions fell by about three quarters, and in a 16-week head-to-head trial ivermectin was more effective than metronidazole 0.75%. The compounded combination itself has not been studied as a product; a licensed doctor weighs this before prescribing.
How it works in the body
Ivermectin acts on Demodex mites, which are more numerous in rosacea skin, and has direct anti-inflammatory effects. Metronidazole reduces inflammation around the follicle. Niacinamide supports the skin barrier so the face becomes less reactive to triggers.
How it helps
How it clears papules and pustules.
Targets Demodex and inflammation
Ivermectin addresses one of the drivers of papulopustular rosacea, not only the surface.
Two authorised actives
Ivermectin and metronidazole both have high-certainty evidence for reducing papules and pustules.
Gentle vehicle
Niacinamide in a light gel suits reactive rosacea skin.
What to expect
Once a day, judged at 12 weeks.
Apply a pea-sized amount once a day to clean, dry skin, spread thinly over the affected areas. Avoid the eyes and lips. Pair it with a gentle cleanser, a non-comedogenic moisturiser and SPF 50+ in the morning.
- Weeks 1-2 · Once daily; a brief flare can happen as mites die off
- Weeks 3-4 · Lesions begin to reduce; irritation settles
- Weeks 4-12 · Continue once daily; compare photos at 8 weeks
- Month 3 · Doctor review; maintenance or step-up plan
Formula your doctor can prescribe
- Standard formulaIvermectin 1% + metronidazole 0.75% + niacinamide 2%, 30 g
Your schedule is personal
These are typical steps only. Your doctor adjusts the plan to how you respond and tolerate it — and you can message them at any point.
Safety first
Safety, in full.
Compounded rosacea spot formula is an effective medicine — and like any medicine it carries risks. Your doctor screens for all of this before prescribing. Here's the honest picture, not just reassurance.
Burning, itching or dryness at the application site are the most frequent effects of both ivermectin and metronidazole and are usually mild. A short-lived increase in spots in the first 2 weeks can occur.
Not suitable if you
- Are allergic to ivermectin, metronidazole, niacinamide or any excipient
- Are pregnant or breastfeeding without an individual decision from your doctor
- Have broken, eczematous or sunburnt skin in the treatment area
- Have lesions that may be acne, perioral dermatitis or an infection that has not been assessed
When to seek urgent care
For severe, sudden or unexpected symptoms, call your local emergency number or go to the nearest emergency department. Then let your doctor know through your account chat.
PRICING
You only pay if treatment is approved.
€25/month for weight loss or €15/month (billed €45 every 90 days) for hair growth. €35 one-off is available for sexual health.
Weight loss
ONGOING PLAN
€25/month
Billed €25 every 28 days · cancel anytime
28-day treatment cycle
For ongoing treatment and doctor-reviewed renewals.
Renewals reviewed by your doctor
Start consultation
Full refund if a review is not approved
WHAT'S INCLUDED
- First consultation included
- Renewals reviewed by your doctor
- Ongoing care with your doctor
- Cancel anytime
Hair growth
ONGOING PLAN
€15/month
Billed €45 every 90 days · cancel anytime
For ongoing treatment and doctor-reviewed renewals.
Lowest monthly price we offer
Start consultation
Full refund if a review is not approved
WHAT'S INCLUDED
- First consultation included
- Renewals reviewed by your doctor
- Ongoing care with your doctor
- Cancel anytime
Sexual health
ONE-OFF
€35 one-off
One consultation, one doctor, one decision.
Nothing stored publicly, ever
Start consultation
Full refund if a review is not approved
WHAT'S INCLUDED
- Consultation reviewed by an EU-licensed doctor
- Electronic prescription if approved
- Full refund if not approved
Full refund if a review is not approved
For a one-off consultation, we refund the €35 consultation fee. For a subscription review, we refund that period's fee and cancel the plan.
Note: The medication, if the doctor prescribes it, is paid separately at the pharmacy at the price it sets. Hi-Doctor does not sell medications.
HOW THE DOCTOR DECIDES
A licensed doctor reviews your case, not an algorithm
An EU-licensed doctor reads your questionnaire and answers in less than 2 hours on average.
If the doctor decides it is not safe to prescribe, the consultation fee is refunded in full.
Follow-up happens in the private chat inside your account, under GDPR. No WhatsApp, no SMS.
FREQUENTLY ASKED QUESTIONS
Questions about Compounded rosacea spot formula.
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Find out if it's right for you
See if Compounded rosacea spot formula is appropriate for you.
Answer a few questions and a licensed EU doctor reviews your case in less than 2 hours on average. Refunded in full if it's not right for you.