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Unbranded clinical vial representing investigational Retatrutide; no marketed pack exists.
Retatrutide · Mosta

Retatrutide in Mosta: what you should know. 

INVESTIGATIONAL · PHASE 3Retatrutide is not approved in the EU and cannot be prescribed here.

We don't prescribe it today, but our doctors can review your case and propose an equivalent weight management treatment with EU approval and clinical evidence.

€25/month (billed €25 every 28 days)Full refund if a review is not approved

IN PLAIN TERMS

What Retatrutide is, and how to get treatment

Retatrutide is an experimental once-weekly injection for weight management. It copies three hormones your body already makes: two gut hormones that tell your brain you are full and help steady your blood sugar, plus a third involved in how you burn stored energy. Most approved medicines act on one or two of these — retatrutide acts on three, which is why it is described as a "triple agonist".

Retatrutide is still being studied. No medicines regulator anywhere has approved it, so it is not made for sale, no pharmacy stocks it, and no doctor in the EU can prescribe it — including us. That is the law, not a limitation of any one clinic.

Learn more about peptides at Peptidepedia.

Can I get it?

Not yet, and not from anyone in the EU. Retatrutide has no marketing authorisation, so it cannot legally be prescribed or dispensed here outside a clinical trial.

Why buying it online is risky

What can I take instead?

Mounjaro is approved in the EU, has published peer-reviewed trial results, and can be prescribed today if a doctor decides it suits you.

Read about Mounjaro

What do the studies show?

Every trial behind Retatrutide is listed below with its registry number, how many people took part, and whether the results are peer-reviewed or a company announcement.

Jump to the studies

Local consultation facts

Can I get Retatrutide in Mosta?

No. Retatrutide is not approved and cannot be prescribed in Mosta, Malta, outside a clinical trial. This is the same EU-wide legal position that applies to every provider. Hi-Doctor can assess EU-approved weight-management options instead.

Availability

Retatrutide has no EU marketing authorisation, approved pack or legitimate pharmacy stock.

Country
Malta
Language of service
Spanish and English
LEGAL STATUS
Investigational · cannot be prescribed
Honoured locally
PDF EU prescription for an approved treatment

How the EU prescription works where you are: For an approved alternative, the EU prescription is supplied as a PDF for use in Malta. It is issued only if the doctor approves treatment.

THE APPROVED ROUTE

Mounjaro: an EU-authorised option.

Mounjaro has been authorised in the EU since 15 September 2022. A licensed doctor can assess whether it is appropriate, and a prescription follows only if the doctor approves.

These are Mounjaro's own trial results. Results for Retatrutide may come from a different dose, duration and patient group, so the figures should not be treated as a direct comparison.

WHAT IT COSTS

One plan, reviewed by a doctor.

Weight loss

ONGOING PLAN

€25/month

Billed €25 every 28 days · cancel anytime

28-day treatment cycle

For ongoing treatment and doctor-reviewed renewals.

Renewals reviewed by your doctor

Start consultation

Full refund if a review is not approved

WHAT'S INCLUDED

  • First consultation included
  • Renewals reviewed by your doctor
  • Ongoing care with your doctor
  • Cancel anytime

Full refund if a review is not approved

If a review is not approved, we refund that period's €25 fee and cancel the plan.

Read the refund terms

Note: The medication, if the doctor prescribes it, is paid separately at the pharmacy at the price it sets. Hi-Doctor does not sell medications.

VERIFIED EVIDENCE

Retatrutide: evidence and regulatory guide.

Retatrutide is a Phase 3 investigational medicine. Some trials have reported results, while direct-comparison and long-term outcome studies are still running.

WHAT IT IS

How it works

A once-weekly triple agonist that activates GIP, GLP-1 and glucagon receptors. The glucagon component distinguishes it from approved dual or single agonists.

  • GIP
  • GLP-1
  • glucagon

DEVELOPMENT STAGE

Phase 3, partially read out

TRIUMPH-1, -2, -3 and -4 and TRANSCEND-T2D-1 have read out. TRIUMPH-5 is still comparing retatrutide with tirzepatide, and cardiovascular and kidney outcomes remain unknown until the outcomes study completes.

Trial register7 registered trials

Every NCT identifier links to its ClinicalTrials.gov record. A readout is not the same as peer-reviewed publication.

Registered trials for Retatrutide
TRIAL / NCTPOPULATIONPARTICIPANTSSTATUSREADOUT / COMPLETION
TRIUMPH-4NCT05931367Obesity or overweight with knee osteoarthritis445Read out2025-12-11
TRIUMPH-1NCT05929066Obesity without type 2 diabetes2,335Read out2026-05-21
TRIUMPH-2NCT05929079Type 2 diabetes1,152Read out2026-07-23
TRIUMPH-3NCT05882045Severe obesity and cardiovascular disease1,946Read out2026-07-23
TRANSCEND-T2D-1NCT06354660Type 2 diabetes537Read out2026-06-13
TRIUMPH-5NCT06662383Head-to-head with tirzepatide800Running2026-11
Cardiovascular and kidney outcomesNCT06383390Cardiovascular and kidney outcomes10,000Running2029-02

What the studies reported

Results are grouped by source and evidence grade so journal data and manufacturer announcements cannot be confused.

Peer-reviewed
Jastreboff et al., NEJM 2023;389(6):514-526 · DOI: 10.1056/NEJMoa2301972
Jastreboff et al., NEJM 2023;389(6):514-526 · DOI: 10.1056/NEJMoa2301972
DOSE OR GROUPMEAN WEIGHT CHANGEWEEKS
Placebo−2.1%48
1 mg−8.7%48
4 mg−17.1%48
8 mg−22.8%48
12 mg−24.2%48

Peer-reviewed Phase 2, N=338, 48 weeks; people with type 2 diabetes were excluded. A trial average is not an individual forecast.

Manufacturer press release — not peer-reviewed
Eli Lilly TRIUMPH-1, TRIUMPH-2 and TRIUMPH-3 releases
Eli Lilly TRIUMPH-1, TRIUMPH-2 and TRIUMPH-3 releases
DOSE OR GROUPMEAN WEIGHT CHANGEWEEKS
TRIUMPH-1 placebo−2.2%80
TRIUMPH-1 · 4 mg−19.0%80
TRIUMPH-1 · 9 mg−25.9%80
TRIUMPH-1 · 12 mg−28.3%80
TRIUMPH-2 · 12 mg−20.8%
TRIUMPH-3 · 12 mg−22.6%

Manufacturer releases, not peer-reviewed. TRIUMPH-1 included about 2,300 people without diabetes; TRIUMPH-2 and -3 studied different populations.

NAMED SAFETY SIGNALS

What has been reported with Retatrutide.

The most common adverse events were gastrointestinal, dose-related and mostly mild to moderate. These additional signals are worth naming plainly.

Dysesthesia

Burning or tingling skin sensations: 12.5% at 12 mg versus 0.9% with placebo.

Heart-rate increase

The increase was dose-dependent and peaked at 24 weeks in Phase 2.

Stopped because of adverse events

11.3–13.5% at the top dose, roughly double placebo.

These are study observations, not a complete safety profile. Retatrutide has no EU-approved product information, and long-term outcomes are still being studied.

UNAPPROVED PRODUCTS ONLINE

Why buying Retatrutide online is not a shortcut.

Retatrutide is not manufactured for an authorised market: there is no approved pack, SmPC or legitimate pharmacy stock. Products sold online are not the approved medicine.

has not been found safe and effective for any conditionUS FOOD AND DRUG ADMINISTRATION

10 → 26

FDA adverse-event reports naming retatrutide: 10 in all of 2025, then 26 in the first five months of 2026.

11 + 3

In those first five months of 2026: 11 hospitalisations and 3 life-threatening reports.

71 / 179

Vendors rated poor, bad or fraud: 71 of 179 assessed, or 39.6%.

Check the EU common logo

A legitimate online pharmacy in the EU must display the common logo linked to its national register. The logo is a verification check; it cannot make an unapproved medicine legal.

How the EU common logo works

EVIDENCE QUESTIONS

Questions about Retatrutide.

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