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Sexual health · TREATMENT GUIDE

Vardenafil guide

On-demand use of prescribed vardenafil for erectile dysfunction, with timing, food, and safety advice.

2 min read · Reviewed by Dr. Alejandro Infante
TREATMENT GUIDE · Sexual health

Vardenafil guide

On-demand use of prescribed vardenafil for erectile dysfunction, with timing, food, and safety advice.

READ TIME
2 min read
PATHWAY
Vardenafil 5/10/20mg

This guide does not replace the package leaflet or your doctor's assessment.

Medicines and interactions to reviewYou use nitrates, nitric oxide donors such as poppers, or riociguat

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Electronic prescription

Sent to the pharmacy you choose; each pharmacy decides whether it can dispense it.

On this page
01

How to use

  1. Take one tablet about 25-60 minutes before activity

    Swallow the tablet whole with water. Use only the prescribed 5 mg, 10 mg, or 20 mg strength. Vardenafil works only with sexual stimulation.

  2. Avoid high-fat meals and grapefruit

    A high-fat meal delays absorption. Grapefruit juice can increase side effect risk. Do not exceed one dose in 24 hours.

  3. Never combine with nitrates or riociguat

    Do not take vardenafil with nitrate medicines, nitric oxide donors such as poppers, or riociguat. The combination can cause a dangerous fall in blood pressure.

Monitoring

Medicines and interactions to review. You use nitrates, nitric oxide donors such as poppers, or riociguat Alpha-blockers, strong CYP3A4 inhibitors, other erectile-dysfunction medicines, and grapefruit need review

02

Dose schedule

  1. As needed, not more than once daily

    Take only when sexual activity is planned. Do not combine with other PDE5 inhibitors.

  2. Review effectiveness

    If ineffective after several properly timed attempts, discuss with the prescriber before changing dose.

03

Side effects

Common vascular effects

Headache, facial flushing, nasal congestion, indigestion, and dizziness. Usually mild and settle as the medicine wears off.

Prolonged erection

A prolonged or painful erection is rare and needs urgent treatment. Bluish tint or blurred vision can occur.

04

Do not use if

  • You use nitrates, nitric oxide donors such as poppers, or riociguat
  • A clinician has advised that sexual activity is unsafe because of a heart condition
  • You have a serious liver condition, very low blood pressure, or a recent stroke or heart attack that has not been reviewed

If any item may apply, do not use the medicine until a clinician has reviewed it.

05

When to contact your doctor

  • An erection that does not go away, sudden loss of vision or hearing, chest pain, collapse, or a severe allergic reaction: seek urgent care
  • Marked dizziness, fainting, palpitations, or a headache that is severe or persistent
  • The prescribed dose is not suitable or does not provide a satisfactory response after several correctly timed attempts
06

Storage

Keep in the original package, away from moisture and direct heat, and out of children's reach. Follow the temperature limit on your pack and do not use it after the expiry date.

07

What to expect

Erectile dysfunction treatments work in most cases but not every attempt. The medicine requires sexual arousal. Several tries may be needed.

08

Sources

Sexual healthThis guide is for patients whose doctor has already prescribed Vardenafil.Questions about your treatment? Message your doctor from your account. Not on treatment yet? An EU-licensed doctor assesses your case and decides whether any treatment is appropriate.Start consultationThis guide does not replace the package leaflet or your doctor's assessment.
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FAQS

Common questions

Vardenafil guide3 questions
Who reviews the guides?
Each guide is reviewed by an EU-licensed doctor. It is based on the official product information, cited at the end of each guide.
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The clinical information on this page was reviewed by: Dr. Alejandro Infante, General medicine, on 26 August 2026. Barcelona College of Physicians, no. 080869277 View profile

If the doctor does not approve treatment, we refund the full amount. Every consultation is fully refundable. How refunds work