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Online medical consultation at Hi-Doctor about Rapamycin — illustrative category image, not the product packaging.
Rapamycin · Kaunas

Rapamycin in Kaunas. 

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NOT AVAILABLE TODAY

Hi-Doctor does not prescribe Rapamycin yet.

Our licensed doctors currently focus on three areas with solid clinical evidence and a clear EU regulatory framework. We extend the catalogue as specialists join and regulation allows. Rapamycin is outside the current scope.

Buying Rapamycin online without a valid prescription carries counterfeiting and toxicity risks. Always consult a licensed healthcare professional.

IN PLAIN TERMS

What Rapamycin is, and how to get treatment

Rapamycin — its medicine name is sirolimus, sold as Rapamune — is an immunosuppressant. It quiets the immune system so it does not attack a transplanted kidney, and that, along with a rare lung condition called sporadic lymphangioleiomyomatosis, is what it is authorised for in the EU. You may have seen it discussed online as an anti-ageing or "longevity" drug: no regulator anywhere has approved it for that, and that use is entirely off-label and unproven. Because it suppresses the immune system it carries real infection and cancer risks and is only prescribed under specialist supervision — Hi-Doctor treats hair loss, weight management and sexual health, and does not prescribe it.

Rapamycin has been authorised for use in the EU since 13 March 2001, so a licensed doctor can prescribe it when it is clinically appropriate for you.

Can I get it?

Yes, if a doctor decides it is right for you. Rapamycin is authorised in the EU and can be prescribed after a medical review.

What can I take instead?

Our doctors review every option and recommend what fits your history and goals.

What do the studies show?

Every trial behind Rapamycin is listed below with how many people took part and whether the results are peer-reviewed or a company announcement.

Jump to the studies

WHAT WE DO COVER

If your question fits one of these three areas, a licensed doctor reviews it in less than 2 hours on average for €35.

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VERIFIED EVIDENCE

Rapamycin: evidence and regulatory guide.

WHAT IT IS

How it works

Blocks a cell-growth signal called mTOR, which damps down the immune cells that would otherwise attack a transplanted organ.

  • mTOR (via FKBP12)

DEVELOPMENT STAGE

EU-authorised medicine

Trial register1 registered trials

Every NCT identifier links to its ClinicalTrials.gov record. A readout is not the same as peer-reviewed publication.

Registered trials for Rapamycin
TRIAL / NCTPOPULATIONPARTICIPANTSSTATUSREADOUT / COMPLETION
Rapamune US Study (sirolimus vs azathioprine in kidney transplantation)Recipients of a primary HLA-mismatched cadaveric or living-donor kidney transplant, all on ciclosporin and prednisone (284 sirolimus 2 mg, 274 sirolimus 5 mg, 161 azathioprine)719Read out2000-07-15

What the studies reported

Results are grouped by source and evidence grade so journal data and manufacturer announcements cannot be confused.

Peer-reviewed
Kahan BD; Rapamune US Study Group. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. Lancet 2000;356(9225):194-202. doi:10.1016/S0140-6736(00)02480-6
Kahan BD; Rapamune US Study Group. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. Lancet 2000;356(9225):194-202. doi:10.1016/S0140-6736(00)02480-6
DOSE OR GROUPMEAN WEIGHT CHANGEWEEKS
sirolimus 2 mg dailyBiopsy-confirmed acute rejection 16.9%, versus 29.8% on azathioprine (p=0.002)26
sirolimus 5 mg dailyBiopsy-confirmed acute rejection 12.0%, versus 29.8% on azathioprine (p<0.001)26

This was a transplant trial in people already taking ciclosporin and prednisone after a kidney transplant. It is not evidence about ageing, healthspan or anything else.

NAMED SAFETY SIGNALS

What has been reported with Rapamycin.

Immunosuppression

Sirolimus deliberately suppresses the immune system. Infections are among the most common side effects, and long-term immunosuppression carries an increased risk of lymphoma and skin cancer.

Impaired wound healing

Delayed or impaired healing, including fluid collections around the graft (lymphocele), is a recognised effect.

Blood and metabolic effects

Reduced blood cell counts, low potassium and phosphate, raised cholesterol and triglycerides, raised blood glucose and a risk of diabetes.

Longevity use is off-label and unproven

No medicines regulator has authorised sirolimus for ageing, longevity or healthspan anywhere. The EU authorisation covers only prophylaxis of kidney-transplant rejection and sporadic lymphangioleiomyomatosis. There is no completed regulatory-grade trial showing it extends healthy life in people who are well, and it requires blood-level monitoring.

Allergen in the oral solution

The oral solution contains soya oil and must be avoided by people allergic to peanut or soya.

HOW IT WORKS · 5 STEPS

Five steps. No waiting room.

From the online consultation to ongoing follow-up — without leaving home.

  1. 5 minutes

    Start your online visit

    Answer a 5-minute health questionnaire from home.

  2. Less than 2 hours

    A doctor reviews your case

    A licensed doctor reviews your answers and replies personally.

  3. Refund guarantee

    Review and payment

    If not approved, we refund your €35 one-off in full.

  4. EU pharmacies

    Collect treatment from the pharmacy

    Collect it at any EU pharmacy with your e-prescription.

  5. 4-week check-in

    Ongoing support

    Private chat, 4-week check-in, simple prescription renewal.

NOTIFY ME

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FREQUENTLY ASKED QUESTIONS

Questions about Rapamycin.

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