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Smoking cessation · TREATMENT GUIDE

Cytisine guide

How to take cytisine to help stop smoking, with the reducing-dose schedule and quit date alignment.

2 min read · Reviewed by Dr. Alejandro Infante
TREATMENT GUIDE · Smoking cessation

Cytisine guide

How to take cytisine to help stop smoking, with the reducing-dose schedule and quit date alignment.

READ TIME
2 min read
PATHWAY
Smoking cessation

This guide does not replace the package leaflet or your doctor's assessment.

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Electronic prescription

Sent to the pharmacy you choose; each pharmacy decides whether it can dispense it.

On this page
01

How to use

  1. Follow the reducing-dose schedule on the pack

    Cytisine is taken 6 times daily initially, then reduced over the 25-day course. Stop smoking no later than day 5 of treatment. Swallow tablets whole with water.

  2. Stop smoking no later than day 5

    The schedule requires you to stop smoking completely no later than day 5. Continue taking the tablets at the reducing doses after you stop.

02

Dose schedule

  1. Days 1-3: 1 tablet 6 times daily

    Take every 2 hours during waking hours. Reduce smoking gradually with the goal to stop completely by day 5.

  2. Days 4-25: follow each reduction stage

    Days 4-12: 1 tablet every 2.5 hours, up to 5 daily; days 13-16: 1 every 3 hours, up to 4 daily; days 17-20: 1 every 5 hours, up to 3 daily; days 21-25: 1-2 tablets daily.

03

Side effects

Gastrointestinal and taste effects

Dry mouth, nausea, changes in taste, and abdominal discomfort are the most common. Usually mild and temporary.

Headache, dizziness, and sleep changes

Headache, dizziness, insomnia, and unusual dreams can occur. These are generally mild.

04

When to contact your doctor

  • Severe nausea, vomiting, or breathing difficulty
  • Chest pain, irregular heartbeat, or severe headache
05

Storage

Keep in the original package, away from moisture and direct heat, and out of children's reach. Follow the temperature limit on your pack and do not use it after the expiry date.

06

What to expect

Cytisine helps reduce nicotine cravings. Stop smoking no later than day 5 and follow the full reducing schedule. Behavioural support is also recommended.

07

Sources

Smoking cessationThis guide is for patients whose doctor has already prescribed Cytisine (cytisinicline).Questions about your treatment? Message your doctor from your account. Not on treatment yet? An EU-licensed doctor assesses your case and decides whether any treatment is appropriate.Start consultationThis guide does not replace the package leaflet or your doctor's assessment.
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FAQS

Common questions

Cytisine guide3 questions
Who reviews the guides?
Each guide is reviewed by an EU-licensed doctor. It is based on the official product information, cited at the end of each guide.
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The clinical information on this page was reviewed by: Dr. Alejandro Infante, General medicine, on 26 August 2026. Barcelona College of Physicians, no. 080869277 View profile

If the doctor does not approve treatment, we refund the full amount. Every consultation is fully refundable. How refunds work