Can I get it?
Yes, if a doctor decides it is right for you. Isotretinoin is authorised in the EU and can be prescribed after a medical review.
Isotretinoin · Limassol
Isotretinoin in Limassol.
Not in our consultation yet. We are continuously onboarding new specialists — leave your email and we'll notify you, or explore the three areas we already cover.
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NOT AVAILABLE TODAY
Hi-Doctor does not prescribe Isotretinoin yet.
Our licensed doctors currently focus on three areas with solid clinical evidence and a clear EU regulatory framework. We extend the catalogue as specialists join and regulation allows. Isotretinoin is outside the current scope.
Buying Isotretinoin online without a valid prescription carries counterfeiting and toxicity risks. Always consult a licensed healthcare professional.
IN PLAIN TERMS
What Isotretinoin is, and how to get treatment
Isotretinoin — widely known by the brand name Roaccutane, and as Accutane outside the EU — is a vitamin-A-derived capsule authorised in EU countries for severe acne: the nodular or scarring kind that has not cleared with antibiotics. It works by shrinking the skin's oil glands. It causes severe birth defects, so in the EU anyone who could become pregnant can only take it inside a formal Pregnancy Prevention Programme, with pregnancy tests before, during and after treatment and effective contraception throughout. It is a genuine, licensed medicine that belongs with a dermatologist; Hi-Doctor treats hair loss, weight management and sexual health, and does not treat acne.
Isotretinoin is an authorised medicine in the EU, so a licensed doctor can prescribe it when it is clinically appropriate for you.
What can I take instead?
Our doctors review every option and recommend what fits your history and goals.
What do the studies show?
Every trial behind Isotretinoin is listed below with how many people took part and whether the results are peer-reviewed or a company announcement.
Jump to the studiesWHAT WE DO COVER
If your question fits one of these three areas, a licensed doctor reviews it in less than 2 hours on average for €35.
TREATMENTS
Three categories, one process.
Choose what fits. The journey is identical.
ONGOING PLANWeight loss
A medical consultation on your weight goal. Treatment if appropriate.
€25/month28-day treatment cycle
Explore weight lossONE-OFFSexual health
An absolutely discreet consultation for intimate concerns.
€35 one-offFull refund if not approved
Explore sexual healthONGOING PLANHair growth
Medical assessment and tailored treatment for hair loss.
€15/monthBilled €45 every 90 days
Explore hair growthLicensed EU doctors
Doctor review in less than 2 hours on average
50,000+ patients served
Secure patient account
VERIFIED EVIDENCE
Isotretinoin: evidence and regulatory guide.
WHAT IT IS
How it works
A vitamin-A-derived capsule that shrinks the skin's oil glands and reduces the blockage and inflammation behind severe acne.
DEVELOPMENT STAGE
EU-authorised medicine
Trial register1 registered trials
Every NCT identifier links to its ClinicalTrials.gov record. A readout is not the same as peer-reviewed publication.
| TRIAL / NCT | POPULATION | PARTICIPANTS | STATUS | READOUT / COMPLETION |
|---|---|---|---|---|
| Peck et al. — 13-cis-retinoic acid in cystic and conglobate acne | Adults with treatment-resistant cystic and conglobate acne | 14 | Read out | 1979-02-15 |
What the studies reported
Results are grouped by source and evidence grade so journal data and manufacturer announcements cannot be confused.
Peer-reviewed
Peck GL, Olsen TG, Yoder FW, et al. Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid. N Engl J Med 1979;300(7):329-333. doi:10.1056/NEJM197902153000701| DOSE OR GROUP | MEAN WEIGHT CHANGE | WEEKS |
|---|---|---|
| average 2.0 mg/kg/day for four months | 13 of 14 patients cleared completely; the remaining patient improved by 75% | — |
This landmark study was very small (14 patients) and uncontrolled; modern EU practice uses lower doses, reserves isotretinoin for severe acne that has not responded to antibiotics, and requires dermatology supervision.
Sources
Last reviewed 2026-07-27
NAMED SAFETY SIGNALS
What has been reported with Isotretinoin.
Severe birth defects (teratogenicity)
Isotretinoin is highly teratogenic and must never be taken during pregnancy. In the EU it may only be given to people who can become pregnant under a Pregnancy Prevention Programme: pregnancy tests before, during and after stopping treatment, at least one effective method of contraception during and after treatment, and a signed acknowledgement form plus a patient reminder card. These measures were reinforced by the EMA retinoid review completed on 22 March 2018.
Mood and behaviour
The 2018 EU review found the evidence on depression conflicting and could not identify a clear increase in risk, but added a precautionary warning: patients should be monitored for changes in mood or behaviour.
Skin and mucous membranes
Dryness of the lips, skin, eyes and nose is the most common effect and is dose-dependent.
Blood tests
Can raise liver enzymes and blood fats (triglycerides and cholesterol), so blood monitoring is part of standard EU prescribing.
Restricted indication
Authorised only for severe forms of acne — nodular or conglobate acne, or acne at risk of permanent scarring — that has failed to respond to standard courses of systemic antibacterials.
HOW IT WORKS · 5 STEPS
Five steps. No waiting room.
From the online consultation to ongoing follow-up — without leaving home.
- 5 minutes
Start your online visit
Answer a 5-minute health questionnaire from home.
- Less than 2 hours
A doctor reviews your case
A licensed doctor reviews your answers and replies personally.
- Refund guarantee
Review and payment
If not approved, we refund your €35 one-off in full.
- EU pharmacies
Collect treatment from the pharmacy
Collect it at any EU pharmacy with your e-prescription.
- 4-week check-in
Ongoing support
Private chat, 4-week check-in, simple prescription renewal.
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