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Tirzepatide vs. Semaglutide: Comparing New Weight Loss Drugs

Get your Semaglutide prescription online from an EU-licensed doctor. We compare Semaglutide and Tirzepatide, two effective weight loss drugs.

25 January 2026
Tirzepatide vs. Semaglutide: Comparing New Weight Loss Drugs

Tirzepatide vs. Semaglutide: Comparing New Weight Loss Drugs

Looking to get a Semaglutide prescription online in the EU? You've landed in the right place. Hi-Doctor connects you with EU-licensed doctors who can review your case and, if appropriate, issue a Semaglutide prescription online. This article compares Semaglutide (Wegovy) and Tirzepatide (Mounjaro), two highly effective weight loss medications. Discover how you can get your medication plan fast: consultation is just €25, and your electronic prescription is issued in under 24 hours, valid at any EU pharmacy.

How it works — get your Semaglutide prescription in 4 steps

  1. Fill the online medical questionnaire (2–3 minutes). Provide your health details securely in our app.
  2. A licensed EU doctor reviews your case in private. Our doctors assess your information to ensure Semaglutide is safe and appropriate for you.
  3. If appropriate, you receive a REMPE electronic prescription within 24 hours. Your prescription is delivered directly to your private account and by email.
  4. Pick up your medication at any EU pharmacy. Your prescription is valid across Spain, Portugal, Italy, Germany, France, and all other EU countries.

Who qualifies for Semaglutide

Semaglutide is a powerful tool for weight management, but it's not for everyone. Our EU-licensed doctors look for specific criteria to ensure patient safety and effectiveness. Generally, you may qualify if you have:

  • A Body Mass Index (BMI) of 30 kg/m² or greater (obesity).
  • A BMI of 27 kg/m² or greater (overweight) with at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol.

Contraindications include a personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a history of pancreatitis. Our doctors carefully assess your full medical history during the online consultation to determine if Semaglutide is the right treatment for you.

What Semaglutide actually does (and doesn't do)

Semaglutide is a GLP-1 receptor agonist. It mimics a natural hormone in your body that regulates appetite and food intake. Here's what it does:

  • Reduces appetite: You feel fuller, faster, and for longer.
  • Slows gastric emptying: Food stays in your stomach longer, helping you feel satisfied.
  • Improves blood sugar control: It stimulates insulin release and suppresses glucagon.

Most patients experience significant weight loss, typically around 15-17% of their initial body weight over 68 weeks when combined with lifestyle changes. However, Semaglutide is not a magic bullet. It works best when partnered with healthy eating and regular physical activity. It doesn't guarantee instant results, and individual outcomes vary.

Side effects and when to stop

Like all medications, Semaglutide can cause side effects. The most common ones are gastrointestinal and tend to be mild to moderate, improving as your body adjusts to the medication:

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Abdominal pain

Your doctor will start you on a low dose and gradually increase it to minimize these effects. If you experience severe or persistent side effects, or any of the following red flags, you should contact a doctor immediately:

  • Severe abdominal pain (could indicate pancreatitis).
  • Symptoms of gallbladder problems (e.g., pain in the upper right abdomen, fever, jaundice).
  • Signs of an allergic reaction (e.g., swelling of the face, lips, tongue, or throat; difficulty breathing).

Always discuss your concerns with an EU-licensed doctor. They will advise if you should adjust your dose or stop treatment.

Why Hi-Doctor vs. walking into a clinic

Choosing Hi-Doctor for your Semaglutide prescription offers significant advantages over traditional clinic visits:

  • Speed: Get your electronic prescription in under 24 hours, compared to weeks for an in-person appointment.
  • Price: A flat €25 for your online consultation. No hidden fees, no variable private clinic costs.
  • Privacy: Everything happens in our secure, RGPD-compliant app. No waiting rooms, no reception desk conversations.
  • Convenience: Access EU-licensed doctors from your phone, anywhere, anytime. No travel, no time off work.
  • Trust: Join over 50,000 satisfied patients. We boast a 4.8 Trustpilot rating.

Our EU-licensed doctors review every case individually, ensuring you receive appropriate, safe, and effective care without the hassle of traditional clinics.

Frequently asked questions

Is it legal to get Semaglutide online in Spain?

Yes, it is legal to get a Semaglutide prescription online from an EU-licensed doctor. Hi-Doctor provides consultations with qualified EU doctors who can legally issue prescriptions valid across all EU member states, including Spain.

How long does the prescription take?

Once you complete your medical questionnaire, an EU-licensed doctor reviews your case. If treatment is deemed appropriate, your REMPE electronic prescription is issued within 24 hours.

Can I use the prescription at any EU pharmacy?

Absolutely. The electronic prescription issued by our EU-licensed doctors is valid at any pharmacy within the European Union, including Spain, Portugal, Italy, France, and Germany.

What happens if the doctor says no?

If, after reviewing your medical information, the doctor determines that Semaglutide is not appropriate or safe for you, they will explain why. You will still be charged the €25 consultation fee for the professional medical review.

Is my data private?

Yes. Hi-Doctor is fully RGPD-compliant. All your medical information and personal data are handled with the strictest confidentiality and security within your private, auditable chat in the app.

How much does it cost?

The online consultation with an EU-licensed doctor is a flat €25. This fee covers the doctor's review of your case and, if appropriate, the issuance of your electronic prescription. The cost of the medication itself is paid directly to the pharmacy.

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