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Tirzepatide vs. Semaglutide: Mounjaro and Wegovy Compared

Looking for Semaglutide or Tirzepatide online in the EU? Get a prescription from an EU-licensed doctor for €25. Reviewed in under 24 hours. Valid at any EU pharmacy. Start your online consultation today.

6 April 2026
Tirzepatide vs. Semaglutide: Mounjaro and Wegovy Compared

Tirzepatide vs. Semaglutide: Mounjaro and Wegovy Compared

Are you searching for an online Semaglutide prescription or Tirzepatide prescription in the EU? You can get a prescription for these medications through an EU-licensed doctor, without an in-person clinic visit. Hi-Doctor offers a flat €25 online consultation. If the doctor finds treatment appropriate, you receive a REMPE electronic prescription within 24 hours, valid at any EU pharmacy (Spain, Portugal, Italy, France, Germany, and more). Everything happens securely in our app, ensuring your privacy and convenience.

How it works — get your Semaglutide prescription in 4 steps

  1. Fill the online medical questionnaire (2–3 minutes). Provide your health details, medical history, and current needs.
  2. A licensed EU doctor reviews your case in private. Our doctors individually assess your information to determine if Semaglutide or Tirzepatide is appropriate for you.
  3. If appropriate, you receive a REMPE electronic prescription within 24 hours. Your prescription is delivered directly to your private account and by email.
  4. Pick up your medication at any EU pharmacy. Your REMPE prescription is universally accepted across the European Union.

Who qualifies for Semaglutide or Tirzepatide

Our EU-licensed doctors carefully review your medical history and current health status. They look for specific criteria to ensure these GLP-1 medications are safe and appropriate for you.

  • Body Mass Index (BMI): Typically, you must have a BMI of 30 kg/m² or higher (obesity), or a BMI of 27 kg/m² or higher (overweight) with at least one weight-related comorbidity such as high blood pressure, type 2 diabetes, or high cholesterol.
  • Medical History: The doctor will assess for conditions like personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or pancreatitis. These are contraindications for GLP-1 agonists.
  • Current Medications: They will check for any potential drug interactions with your existing prescriptions.
  • Overall Health: Your general health, including kidney and liver function, will also be considered.

The doctor remains the gatekeeper, ensuring your safety above all else. If you meet the criteria and the doctor finds it appropriate, a prescription will be issued.

What Semaglutide and Tirzepatide actually do (and doesn't do)

Semaglutide (Wegovy) and Tirzepatide (Mounjaro) are both GLP-1 receptor agonists, a class of medications that mimic a natural hormone in your body. They work by:

  • Slowing Gastric Emptying: Food stays in your stomach longer, making you feel fuller for extended periods.
  • Reducing Appetite: They act on your brain to decrease hunger and cravings.
  • Improving Blood Sugar Control: They help your body release insulin when blood sugar is high and reduce glucose production by the liver.

Tirzepatide has an additional mechanism; it also targets GIP receptors. This dual action can lead to greater weight loss for some individuals compared to Semaglutide alone. While these medications are powerful tools for weight management, they are not magic pills. They work best when combined with lifestyle changes, including a balanced diet and regular physical activity. You will not lose 10 kg in a month, and results vary from person to person. The goal is sustainable, healthy weight loss over time.

Side effects and when to stop

Like all medications, Semaglutide and Tirzepatide can cause side effects. Most common side effects are mild and temporary as your body adjusts to the medication. These include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain

These usually improve over time. It's crucial to follow the doctor's instructions on dosage titration. Red flags that require immediate medical attention include severe abdominal pain (which could indicate pancreatitis or gallbladder issues), persistent vomiting, or symptoms of a severe allergic reaction. If you experience any concerning or severe side effects, you must stop the medication and consult a doctor immediately. Our doctors will guide you through potential side effects and what to look out for.

Why Hi-Doctor vs. walking into a clinic

Choosing Hi-Doctor for your Semaglutide or Tirzepatide prescription offers significant advantages over traditional in-person clinic visits:

  • Speed: Get your prescription review and issuance in under 24 hours with Hi-Doctor, compared to waiting weeks for a clinic appointment.
  • Price: A flat €25 for your online consultation, with no hidden fees or variable private clinic charges.
  • Privacy: Everything happens in the app – no waiting rooms, no reception desks, and no discussing your health with staff in public. Your data is private and RGPD-compliant.
  • Convenience: Complete your consultation from anywhere, anytime, using your phone or computer. No travel to a city-centre clinic.
  • Trust: Join over 50,000 satisfied patients. We boast a 4.8 Trustpilot rating, reflecting our commitment to quality care and patient satisfaction.

Our EU-licensed doctors provide individual case reviews, ensuring you receive appropriate and safe care, all within a fully auditable chat inside your private account.

Frequently asked questions

Is it legal to get Semaglutide online in Spain or other EU countries?

Yes, it is legal to obtain a prescription for Semaglutide or Tirzepatide online through an EU-licensed doctor. Our doctors issue REMPE electronic prescriptions that are valid at any licensed pharmacy across the EU, including Spain, Portugal, Italy, France, and Germany.

How long does the prescription take?

After you complete your medical questionnaire, an EU-licensed doctor reviews your case. If treatment is appropriate, your REMPE electronic prescription is issued in under 24 hours.

Can I use the prescription at any EU pharmacy?

Yes, the REMPE electronic prescription you receive from Hi-Doctor is valid at any licensed pharmacy throughout the European Union.

What happens if the doctor says no?

If the doctor determines that Semaglutide or Tirzepatide is not appropriate or safe for you, no prescription will be issued. In such cases, you will receive a full refund of your €25 consultation fee.

Is my data private?

Absolutely. Hi-Doctor is fully RGPD-compliant. All your medical information and communication with the doctor happen within your private, secure, and auditable in-app chat. We never use WhatsApp or SMS for sensitive health data.

How much does it cost?

The online consultation with an EU-licensed doctor costs a flat €25. This fee covers the doctor's review of your case and, if appropriate, the issuance of your electronic prescription. This does not include the cost of the medication itself, which you pay at the pharmacy.

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