How to Get Epiduo Online in Florence
Need Epiduo in Florence? Complete an online acne consultation with an EU doctor. Receive an official REMPE electronic prescription in under 24 hours if appropriate for your skin.

DIRECT ANSWER
An online consultation lets an EU-licensed doctor review your case and, if appropriate, issue a prescription that is valid across the EU.
Less than 4 hours on average
Prescription issued in less than 4 hours on average if approved.
EU-licensed doctors
Every case is reviewed by a licensed clinician.
Valid across the EU
Approved prescriptions can be used at any EU pharmacy.
In this article
If you want to get Epiduo online in Florence, you do not need to spend weeks waiting for a local dermatologist appointment. Through Hi-Doctor, an EU-licensed doctor reviews your medical history and skin photographs through an asynchronous clinical questionnaire. When clinically appropriate, your doctor issues an official REMPE electronic prescription in under 24 hours, which you can present at local pharmacies across Florence and the wider EU. The consultation costs a one-off fee of 40 EUR, and the 40 EUR consultation fee is refunded in full if the doctor does not issue a prescription.
Over 50,000 patients have accessed asynchronous medical care through Hi-Doctor, backed by a 4.8/5 Trustpilot rating across the European Union.
Key takeaways
- Location-ready: Designed for residents and visitors needing to get Epiduo online in Florence without in-person clinic queues.
- Transparent pricing: A 40 EUR one-off medical review. The consultation fee is refunded in full if the doctor determines treatment is unsuitable.
- Asynchronous assessment: Includes a clinical photo upload step—no video call or live chat required.
- Cross-border prescription: Issued via Spain's REMPE standard under Directive 2011/24/EU for presentation at EU pharmacies.
- Topical treatment scope: Covers mild-to-moderate inflammatory and comedonal acne. Severe nodulocystic acne is referred to in-person care.
How it works — get your consultation in 4 steps
Consulting an EU-licensed doctor for acne treatment takes roughly five minutes from your phone or computer. The entire process is handled asynchronously and securely under GDPR compliance.

- Complete the acne questionnaire: Detail your breakout history, previous treatments, allergies, and current medications.
- Upload clear photos: Provide high-resolution photographs of the affected skin areas so the doctor can assess lesion types and inflammation severity.
- Clinical evaluation: An EU doctor assesses your submission within 24 hours. If treatment is not clinically appropriate, no prescription is issued and your 40 EUR fee is refunded in full.
- Receive your REMPE prescription: If approved, download your electronic prescription PDF directly from your secure account. You can present it at any pharmacy in Florence, where the pharmacist reviews it and may dispense the medication.
Who qualifies
To safely get Epiduo online in Florence, your clinical profile must meet EU prescribing guidelines for topical fixed-dose retinoid and antimicrobial combinations.

| Eligible for Online Review | Requires In-Person Referral |
|---|---|
| Mild-to-moderate comedonal and inflammatory acne | Severe nodulocystic or conglobata acne |
| Adults and adolescents aged 12 and older | Acne with deep scarring or active secondary infections |
| Patients able to upload clear diagnostic photographs | Patients requiring oral isotretinoin or oral antibiotics |
| Non-pregnant, non-breastfeeding individuals | Known hypersensitivity to adapalene or benzoyl peroxide |
Hi-Doctor's dermatology service is strictly topical. If your assessment indicates severe, nodular, or cystic disease, our doctors will refer you to in-person clinical care rather than prescribing online.
What Epiduo actually does
Epiduo is a fixed-dose topical gel combining two active ingredients: adapalene 0.1% and benzoyl peroxide 2.5%. It targets the primary drivers of acne simultaneously without relying on topical antibiotics.
- Adapalene 0.1%: A third-generation topical retinoid that modulates cellular differentiation and keratinisation. It prevents microcomedones from forming, normalises skin cell turnover, and reduces deep inflammation.
- Benzoyl Peroxide 2.5%: A potent antimicrobial agent that generates free radicals to reduce Cutibacterium acnes populations. Because it works via oxidation rather than bacterial metabolic pathways, it does not induce bacterial resistance.
Clinical improvements with adapalene and benzoyl peroxide gel are evaluated at the 12-week mark. Retinoid purging frequently occurs during weeks 2 to 6.
Epiduo is formulated specifically for daily evening application. Note that our formulary covers standard Epiduo (0.1% adapalene / 2.5% benzoyl peroxide); Epiduo Forte (0.3% adapalene) is not offered.
Side effects and when to stop
Local cutaneous reactions are common when initiating topical retinoid therapy. Most side effects peak within the first four weeks and lessen as the skin barrier adapts.
- Expected initial effects: Erythema (redness), scaling, skin dryness, stinging, and mild burning sensations. Using a non-comedogenic moisturiser mitigates these symptoms.
- Photosensitivity: Adapalene increases vulnerability to ultraviolet radiation. Apply a broad-spectrum SPF 30+ daily and avoid direct sun exposure.
- When to discontinue: Stop treatment and consult a healthcare professional immediately if you experience severe contact dermatitis, facial swelling, eyelid oedema, or signs of an allergic reaction.
Why Hi-Doctor vs. walking into a clinic
Navigating the local healthcare system in Florence as an expat, traveller, or busy professional often means lengthy delays for non-urgent dermatology consultations.

| Feature | Hi-Doctor Online Consultation | Traditional Clinic Visit |
|---|---|---|
| Consultation Fee | 40 EUR one-off fee | 80 EUR to 150 EUR+ |
| Turnaround Time | Doctor reviews within 24 hours | Days to weeks for an appointment |
| Format | Asynchronous questionnaire + photo upload | In-person physical attendance |
| Refund Policy | Consultation fee refunded if no prescription issued | Non-refundable visit fee |
| Prescription Type | Official REMPE PDF (Directive 2011/24/EU) | Paper or regional digital script |
COMMON QUESTIONS
Frequently asked questions
Yes. Under EU Directive 2011/24/EU and Commission Implementing Directive 2012/52/EU, cross-border prescriptions containing mandatory prescriber and patient data can be presented at any EU pharmacy. The local pharmacist in Florence reviews the document and may dispense the medication or an equivalent product authorised in Italy. Pharmacists retain the professional discretion to refuse dispensing.





