Posso obtê-lo?
Sim, se um médico decidir que é adequado para si. Saxenda está autorizado na UE e pode ser prescrito após uma avaliação médica.
Um médico licenciado na UE analisa o seu caso e, se for elegível, emite uma receita eletrónica válida em qualquer farmácia da UE ao abrigo da Diretiva 2011/24/UE.

Reembolso total se uma avaliação não for aprovada · A medicação, se for prescrita, é dispensada e paga separadamente numa farmácia.
EM TERMOS SIMPLES
A liraglutida é um medicamento administrado através de uma injeção sob a pele uma vez por dia. Tal como a semaglutida, imita a hormona intestinal natural GLP-1, que avisa o cérebro de que já comeu o suficiente, reduzindo assim a fome e o desejo de comer. Para o controlo do peso na UE, é vendida como Saxenda e utilizada em conjunto com uma alimentação com menos calorias e mais atividade física. Está autorizada na UE para o controlo do peso desde março de 2015.
Saxenda está autorizado para utilização na UE desde 23 de março de 2015. Por isso, um médico habilitado pode prescrevê-lo quando for clinicamente adequado para si.
Saiba mais sobre péptidos em Peptidepedia.
Sim, se um médico decidir que é adequado para si. Saxenda está autorizado na UE e pode ser prescrito após uma avaliação médica.
Os nossos médicos avaliam todas as opções de Perda de peso e recomendam a que melhor se adapta ao seu historial clínico e aos seus objetivos.
Veja todas as opções de Perda de pesoTodos os ensaios sobre Saxenda estão indicados abaixo, com o respetivo número de registo, o número de participantes e a indicação de que os resultados foram revistos por pares ou de que são apenas um anúncio da empresa.
Ir para os estudosEVIDÊNCIA VERIFICADA
O QUE É
It copies the gut hormone GLP-1, which increases the feeling of fullness and reduces hunger and food cravings.
FASE DE DESENVOLVIMENTO
Cada identificador NCT liga ao registo ClinicalTrials.gov. Um resultado comunicado não equivale a uma publicação revista por pares.
| ENSAIO / NCT | POPULAÇÃO | PARTICIPANTES | ESTADO | RESULTADO / CONCLUSÃO |
|---|---|---|---|---|
| SCALE Obesity and Prediabetes (NN8022-1839)NCT01272219 | Adults with a BMI of 30 kg/m² or more, or 27 kg/m² or more with treated high blood pressure or abnormal blood fats, without type 2 diabetes; all received lifestyle counselling | 3,731 | Com resultados | 2015-07-02 |
Os resultados estão separados por fonte e grau de evidência para não confundir dados científicos com anúncios do fabricante.
| DOSE OU GRUPO | ALTERAÇÃO MÉDIA DO PESO | SEMANAS |
|---|---|---|
| 3.0 mg once daily | −8.0% | 56 |
| Placebo | −2.6% | 56 |
Everyone in the trial also received lifestyle counselling, people with type 2 diabetes were excluded, and the primary result covers 56 weeks only.
SINAIS DE SEGURANÇA IDENTIFICADOS
Reported by 40.2% of people on liraglutide 3.0 mg versus 14.7% on placebo in the SCALE Obesity and Prediabetes trial.
Reported by 20.9% on liraglutide 3.0 mg versus 9.3% on placebo in the same trial.
Reported by 20.0% on liraglutide 3.0 mg versus 8.7% on placebo in the same trial.
Reported by 16.3% on liraglutide 3.0 mg versus 4.1% on placebo in the same trial.
Acute gallstone events were reported by 2.3% on liraglutide 3.0 mg versus 0.9% on placebo across the EMA weight-management trial pool, mainly gallstones (1.5% versus 0.5%).
Independently confirmed in 7 people (0.2%) on liraglutide 3.0 mg versus 1 person (under 0.1%) on placebo across the EMA weight-management trial pool.
Serious adverse events were reported in 6.2% of the liraglutide group versus 5.0% of the placebo group in the SCALE Obesity and Prediabetes trial.
EM 60 SEGUNDOS
DADOS DA MARCA
Sobre o tratamento
Saxenda contém a substância ativa liraglutide.
Substância ativa: Liraglutide · Dosagens: 0.6 – 3 mg / day
Liraglutide is a GLP-1 receptor agonist given as a daily subcutaneous injection. It was one of the first in its class approved in Europe for weight management in adults with obesity, or overweight with comorbidities.
Compared with weekly GLP-1s, its daily dosing can be useful when flexibility of adjustment matters or when a semaglutide hasn't been tolerated. The doctor weighs this up in your consultation — two GLP-1 agonists are never combined.
COMO ATUA
Like other GLP-1 analogues, liraglutide mimics a natural gut hormone: it eases hunger signals and produces earlier fullness, so you tend to eat less. Being shorter-acting, its dose is adjusted day by day.
Liraglutide is a copy of a natural gut hormone called GLP-1, which the body releases after eating. The EU product information describes it as an acylated human GLP-1 analogue with 97% amino acid sequence homology to the human hormone, and it binds to and activates the GLP-1 receptor.
GLP-1 receptors also sit in brain regions that regulate appetite. The product information reports that liraglutide increases feelings of fullness and satiety while lowering hunger and prospective food consumption, so people eat less. It does not increase energy expenditure compared with placebo.
Liraglutide has an elimination half-life of roughly 13 hours, which is why it is injected once every day rather than once a week like semaglutide or tirzepatide. It also raises insulin and lowers glucagon in a glucose-dependent way, and weight is lost mainly as fat mass.
Como ajuda
Earlier fullness and calmer hunger signals through the day.
Daily titration lets the doctor fine-tune the dose to your tolerance.
Among the first weight-management GLP-1s approved in Europe.
O que esperar
Treatment starts at a low daily dose and steps up through the intermediate doses as tolerated. Your doctor sets the pace and adjusts if side effects appear.
Typical escalation
NO DIA A DIA
Liraglutide is injected once daily, at any time of day, with or without food. Unlike weekly injections it needs a dose every 24 hours, so it is easiest to pick a convenient time and keep to it.
Treatment starts at 0.6 mg once daily and rises by 0.6 mg at intervals of at least a week, reaching the 3.0 mg maintenance dose in week 5. The slow climb is there to improve stomach and bowel tolerance.
The injection goes under the skin of the abdomen, the thigh or the upper arm. It must never be given into a vein or a muscle. Rotate the site each day to reduce the risk of amyloid deposits building up under the skin.
Look at the liquid before you inject. It should be clear and colourless, or almost colourless. With a new pen, do the flow check described in the instructions so you can see a drop appear at the needle tip before setting your dose.
If you remember within 12 hours of your usual time, take the dose as soon as you can. If there is less than 12 hours until the next one, skip it and carry on as normal. Never take an extra dose.
Unused pens are kept in a refrigerator between 2 and 8 degrees Celsius, away from the freezer compartment, and must not be frozen. A pen in use can be stored below 30 degrees Celsius or refrigerated, and is discarded one month after first use.
Nausea, vomiting and diarrhoea are common at the start and can leave you short of fluid. Dehydration has been linked to kidney impairment and acute kidney failure on GLP-1 medicines, so drink plenty and tell your doctor if you cannot keep fluids down.
Liraglutide is licensed as an addition to a reduced-calorie diet and increased physical activity, not as a replacement for them. Every trial result quoted on this page comes from people doing both alongside the daily injection.
Segurança primeiro
Saxenda é um medicamento eficaz — e, como qualquer medicamento, acarreta riscos. O seu médico verifica tudo isto antes de prescrever. Este é o retrato honesto, não apenas palavras tranquilizadoras.
Stop and get urgent medical help if
seek medical help immediately
these need urgent attention, whatever the frequency
Very common
very common (≥1/10)
more than 1 in 10 people
Common
common (≥1/100 to <1/10)
between 1 in 100 and 1 in 10 people
Uncommon
uncommon (≥1/1,000 to <1/100)
between 1 in 1,000 and 1 in 100 people
Rare
rare (≥1/10,000 to <1/1,000)
between 1 in 10,000 and 1 in 1,000 people
Frequency not known
frequency not known (cannot be estimated from the available data)
reported, but nobody can yet say how often it happens
Adultos com obesidade (IMC ≥30) ou excesso de peso (IMC ≥27) com pelo menos uma condição associada como diabetes tipo 2, hipertensão ou dislipidemia.
QUEM NÃO DEVE TOMAR E QUEM PRECISA DE PRECAUÇÃO
| MEDICAMENTO OU SUBSTÂNCIA | O QUE PODE ACONTECER | O QUE FAZ O MÉDICO |
|---|---|---|
| Insulin and sulfonylureas (for example gliclazide) | Combined use in type 2 diabetes raises the risk of low blood sugar, sometimes severe. | The prescriber may lower the insulin or sulfonylurea dose and asks for blood glucose self-monitoring. |
| Other GLP-1 receptor agonists | Two medicines acting on the same receptor add side effects without an established extra benefit. | Liraglutide for weight management must not be combined with another GLP-1 receptor agonist. |
| Warfarin and other coumarin blood thinners | No interaction study was done, and a clinically relevant effect on warfarin cannot be excluded. | The prescriber arranges more frequent INR checks when liraglutide is started. |
| Oral medicines in general | Liraglutide slightly delays stomach emptying, which can slow how fast a tablet is absorbed. | Interaction studies showed no clinically relevant delay, so no dose change is required. |
| Paracetamol | Peak paracetamol level fell by 31% and was reached up to 15 minutes later; total exposure was unchanged. | No dose adjustment is needed for paracetamol taken alongside liraglutide. |
| Combined oral contraceptives | Peak ethinylestradiol and levonorgestrel levels fell by 12% and 13%, with no relevant change in total exposure. | The contraceptive effect is expected to be unaffected, so no change is required. |
| Atorvastatin, digoxin and lisinopril | Peak levels fell by 38%, 31% and 27% respectively, with only small changes in total exposure. | No dose adjustment of any of these three is required based on those results. |
| General anaesthesia or deep sedation | Delayed stomach emptying can leave food in the stomach, and pulmonary aspiration has been reported. | Tell the anaesthetic team you take liraglutide before any procedure needing anaesthesia or sedation. |
EVIDÊNCIA
The SCALE phase 3 programme tested liraglutide 3.0 mg once daily against placebo in 5,358 adults, and reported a mean body-weight change of -8.0% at 56 weeks compared with -2.6% on placebo.
3,731 adults with BMI >= 30, or >= 27 with dyslipidaemia or hypertension · 56 weeks
SCALE Obesity and Prediabetes. Placebo changed -2.6%. In kilograms the change was -8.4 kg versus -2.8 kg from a mean baseline of 106.3 kg.
Fonte: Saxenda 6 mg/mL solution for injection in pre-filled pen: Annex I Summary of Product Characteristics3,731 adults without type 2 diabetes · 56 weeks
In the same trial 26.6% of the placebo group reached 5%. For a loss of more than 10% the figures were 32.8% and 10.1%.
Fonte: Saxenda 6 mg/mL solution for injection in pre-filled pen: Annex I Summary of Product Characteristics2,254 adults with prediabetes at screening · 160 weeks
Placebo changed -1.8%. The weight loss occurred mainly in the first year and was sustained through week 160.
Fonte: Saxenda 6 mg/mL solution for injection in pre-filled pen: Annex I Summary of Product Characteristics2,254 adults with prediabetes and obesity or overweight · 160 weeks
Estimated time to onset of type 2 diabetes was 2.7 times longer on liraglutide, with a hazard ratio of 0.2 versus placebo.
Fonte: Saxenda 6 mg/mL solution for injection in pre-filled pen: Annex I Summary of Product Characteristics422 adults who had already lost at least 5% on a low-calorie diet · 56 weeks
SCALE Maintenance. Placebo changed -0.2%. 81.4% on liraglutide kept at least 5% of the run-in loss, versus 48.9% on placebo.
Fonte: SCALE Maintenance: weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight lossThese figures are group averages from randomised trials, not a prediction for any one person. Some participants lost far more than the average and some lost very little, and everyone in these trials was also following an energy-restricted diet with exercise counselling alongside the daily injection. The product information also notes that of the people who had lost less than 5% after 12 weeks on the full dose, 93.4% did not go on to reach a 10% loss at one year, which is why the prescriber reviews progress at that point.
ALTERNATIVAS
| MEDICAMENTO | COMO SE ADMINISTRA | COM QUE FREQUÊNCIA | INTERVALO DE DOSE HABITUAL | INDICAÇÃO AUTORIZADA NA UE | EVIDÊNCIA PRINCIPAL |
|---|---|---|---|---|---|
| Semaglutide | Injeção semanal | Uma vez por semana | 0.25–2.4 mg | Adjunct to a reduced-calorie diet and increased physical activity for weight management in adults with BMI ≥30, or ≥27 to <30 with at least one weight-related comorbidity. | STEP 1: mean -14.9% body weight at 68 weeks versus -2.4% placebo |
| Tirzepatide | Injeção semanal | Uma vez por semana | 2.5–15 mg | Adjunct to a reduced-calorie diet and increased physical activity for weight management in adults with BMI ≥30, or ≥27 to <30 with at least one weight-related comorbidity. | SURMOUNT-1: mean -20.9% body weight at 72 weeks versus -3.1% placebo |
| Orlistat | Cápsula oral | Com cada refeição principal | 120 mg per main meal | In conjunction with a mildly hypocaloric diet, for obese patients with BMI ≥30, or overweight patients with BMI ≥28 and associated risk factors. | XENDOS: mean 5.8 kg lost at four years versus 3.0 kg on placebo |
Não sabe qual se adequa ao seu caso? O médico analisa o seu historial e diz-lhe.
Iniciar consulta · 25 €/mêsACESSO E CUSTO
Liraglutide is a centrally authorised medicine that is subject to medical prescription across the European Union, so no pharmacy can supply it without a valid prescription from a doctor. Who pays varies a lot by country: most national health systems do not cover it for weight management, so the patient pays the pharmacy directly. The entries for Spain, Germany, the Netherlands, Portugal, Ireland and Poland come from the national sources listed below; the rows for France, Italy, Belgium and Austria record the general position for this indication and are not confirmed against a national decision. The national database linked on each row is the authority on the current position.
O que paga à Hi-Doctor
25 €/mês (cobrado 25 € a cada 28 dias)
Responda a algumas perguntas e um médico licenciado na UE analisa o seu caso em menos de 2 horas, em média. Reembolso total se não for adequado para si.
O que a farmácia cobra
A Hi-Doctor não vende, não armazena nem dispensa medicamentos e não define o seu preço. O medicamento é pago à parte na farmácia e o valor depende do país, da embalagem, da existência de genérico e da comparticipação. A base de dados oficial ligada na tabela publica o preço autorizado em vigor.
| PAÍS | REGIME DE DISPENSA | COMPARTICIPADO PELO SISTEMA DE SAÚDE? | FONTE OFICIAL |
|---|---|---|---|
| Espanha | Medicamento sujeito a receita médica | Not reimbursed for weight management | AEMPS CIMA |
| Alemanha | Medicamento sujeito a receita médica | Excluded from statutory health insurance as a weight-regulation medicine | PharmNet.Bund AMIce |
|---|---|---|---|
| França | Medicamento sujeito a receita médica | Not reimbursed for weight management | Base de données publique des médicaments |
| Itália | Medicamento sujeito a receita médica | Not reimbursed for weight management | AIFA Medicinali |
| Países Baixos | Medicamento sujeito a receita médica | Restricted, conditions set in Regeling zorgverzekering bijlage 2 | CBG-MEB Geneesmiddeleninformatiebank |
| Portugal | Medicamento sujeito a receita médica | Not reimbursed for weight management | INFARMED Infomed |
| Bélgica | Medicamento sujeito a receita médica | Not reimbursed for weight management | FAGG-AFMPS medicines database |
| Irlanda | Medicamento sujeito a receita médica | Reimbursed by the HSE since January 2023, see national criteria | HPRA Find a Medicine |
| Áustria | Medicamento sujeito a receita médica | Not reimbursed for weight management | BASG Medikamente Info Austria |
| Polónia | Medicamento sujeito a receita médica | Not reimbursed, patient pays in full | Rejestr Produktów Leczniczych |
PREÇOS
25 €/mês para perda de peso ou 15 €/mês (cobrado 45 € a cada 90 dias) para crescimento capilar. Para saúde sexual está disponível uma consulta pontual de 35 €.
PLANO CONTÍNUO
25 €/mês
Cobrado 25 € a cada 28 dias · cancele a qualquer momento
Ciclo de tratamento de 28 dias
Para tratamento contínuo e renovações revistas pelo seu médico.
Renovações revistas pelo seu médico
Reembolso total se uma avaliação não for aprovada
O QUE ESTÁ INCLUÍDO
Reembolso total se uma avaliação não for aprovada
Se uma avaliação não for aprovada, devolvemos a taxa de 25 € desse período e cancelamos o plano.
Nota: A medicação, se o médico a prescrever, é paga separadamente na farmácia ao preço que esta definir. A Hi-Doctor não vende medicamentos.
COMO DECIDE O MÉDICO
Um médico habilitado na UE lê o seu questionário e responde em menos de 2 horas, em média.
Se o médico decidir que não é seguro prescrever, o valor da consulta é reembolsado na íntegra.
O acompanhamento decorre no chat privado da sua conta, em conformidade com o RGPD. Sem WhatsApp, sem SMS.
PERGUNTAS FREQUENTES
OUTROS TRATAMENTOS DE PERDA DE PESO
FONTES
Saxenda (liraglutide): European public assessment report, medicine overview — European Medicines Agency, 2015
Saxenda 6 mg/mL solution for injection in pre-filled pen: Annex I Summary of Product Characteristics — European Medicines Agency, 2026
Saxenda 6 mg/mL solution for injection in pre-filled pen: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Saxenda 6 mg/mL solution for injection in pre-filled pen: Patient Information Leaflet — electronic medicines compendium (emc), 2026
Liraglutide (Saxenda, Diavic, Zegluxen): NHS medicines A to Z — NHS, 2026
SCALE Obesity and Prediabetes: a randomized, controlled trial of 3.0 mg of liraglutide in weight management — New England Journal of Medicine, 2015
SCALE Maintenance: weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss — International Journal of Obesity, 2013
Victoza (liraglutide): European public assessment report, medicine overview — European Medicines Agency, 2009
Saxenda (liraglutide) injection: US prescribing information, boxed warning and contraindications — DailyMed, US National Library of Medicine, 2026
CIMA: Saxenda presentations, marketing and prescription status in Spain — AEMPS (Spanish Agency of Medicines and Medical Devices), 2026
Sozialgesetzbuch V § 34: medicines excluded from statutory health insurance, including those for weight regulation — Bundesministerium der Justiz (gesetze-im-internet.de), 2026
Liraglutide: preparaattekst and vergoeding conditions in the Netherlands — Farmacotherapeutisch Kompas, Zorginstituut Nederland, 2026
Liraglutide (Saxenda): health technology assessment and HSE reimbursement decision — National Centre for Pharmacoeconomics (Ireland), 2023
Rejestr Produktow Leczniczych: Saxenda registration record in Poland — Centrum e-Zdrowia (Poland), 2026
INFOMED: base de dados de medicamentos de uso humano — INFARMED (Portugal), 2026
STEP 1: Once-weekly semaglutide in adults with overweight or obesity — New England Journal of Medicine, 2021
SURMOUNT-1: Tirzepatide once weekly for the treatment of obesity — New England Journal of Medicine, 2022
XENDOS: XENical in the prevention of Diabetes in Obese Subjects, a 4-year randomised study — Diabetes Care, 2004
Wegovy (semaglutide) solution for injection: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Xenical 120 mg hard capsules: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Revisto pela equipa médica da Hi-Doctor · Última revisão 2026-07-27 · Próxima revisão prevista em 2027-07-27
Esta página contém informação sobre um medicamento; não é uma recomendação para o tomar nem substitui uma consulta médica. Só um médico habilitado que tenha analisado o seu historial pode decidir se um tratamento é adequado para si.
Descubra se é adequado para si
Responda a algumas perguntas e um médico licenciado na UE analisa o seu caso em menos de 2 horas, em média. Reembolso total se não for adequado para si.
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