Posso ottenerlo?
Sì, se un medico ritiene che sia adatto a Lei. Sildenafil è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
Un medico autorizzato dall'UE esamina il Suo caso e, se idoneo, rilascia una prescrizione elettronica valida in qualsiasi farmacia dell'UE ai sensi della direttiva 2011/24/UE.

Rimborso completo se una valutazione non viene approvata · Il farmaco, se prescritto, viene dispensato e pagato separatamente in farmacia.
IN PAROLE SEMPLICI
Sildenafil è una compressa con obbligo di ricetta per la disfunzione erettile, autorizzata per la prima volta in tutta l’UE nel 1998. Rilassa i vasi sanguigni del pene, così può affluire più sangue quando è sessualmente eccitato. Non crea eccitazione da solo: la stimolazione sessuale è comunque necessaria perché funzioni. Di solito si assume circa un’ora prima del rapporto sessuale e non può essere usato insieme a medicinali nitrati per il cuore.
Sildenafil è autorizzato per l’uso nell’UE dal 13 settembre 1998. Un medico abilitato può quindi prescriverlo quando è clinicamente adatto a Lei.
Sì, se un medico ritiene che sia adatto a Lei. Sildenafil è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
I nostri medici esaminano ogni opzione per Salute sessuale e consigliano quella più adatta alla Sua storia clinica e ai Suoi obiettivi.
Veda tutte le opzioni per Salute sessualeTutti gli studi su Sildenafil sono elencati qui sotto con il numero di partecipanti e l’indicazione se i risultati sono stati sottoposti a revisione paritaria o provengono da un annuncio dell’azienda.
Vada agli studiEVIDENZE VERIFICATE
CHE COS’È
Sildenafil blocks an enzyme called PDE5 that normally ends an erection, so when a man is sexually aroused the blood vessels in the penis stay relaxed and more blood can flow in.
FASE DI SVILUPPO
Ogni identificativo NCT rimanda al record ClinicalTrials.gov. Una comunicazione dei risultati non equivale a una pubblicazione sottoposta a revisione paritaria.
| STUDIO / NCT | POPOLAZIONE | PARTECIPANTI | STATO | RISULTATO / COMPLETAMENTO |
|---|---|---|---|---|
| Sildenafil Study Group — 24-week dose-response study | Men with erectile dysfunction of organic, psychogenic and mixed causes | 532 | Con risultati | 1998-05-14 |
| Sildenafil Study Group — 12-week flexible dose-escalation study | Men with erectile dysfunction of organic, psychogenic and mixed causes | 329 | Con risultati | 1998-05-14 |
| Sildenafil Study Group — 32-week open-label extension | Men continuing from the dose-escalation study | 225 | Con risultati | 1998-05-14 |
I risultati sono separati per fonte e grado di evidenza, così i dati scientifici non vengono confusi con gli annunci del produttore.
| DOSE O GRUPPO | VARIAZIONE MEDIA DEL PESO | SETTIMANE |
|---|---|---|
| 100 mg | Mean score on the IIEF question about achieving erections rose from 2.0 to 4.0 out of a possible 5 | 24 |
| 25-100 mg, flexible | 69% of intercourse attempts successful vs 22% on placebo (final 4 weeks) | 12 |
| 25-100 mg, flexible | 5.9 successful attempts per month vs 1.5 on placebo | 12 |
Both studies were short (12 and 24 weeks) and relied on self-reported questionnaires and diaries, so they describe short-term effect rather than long-term outcomes.
SEGNALI DI SICUREZZA IDENTIFICATI
Listed as very common in the EU product information — at least 1 in 10 men. In the pivotal trial, headache, flushing and dyspepsia were the most common effects, occurring in 6% to 18% of men.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men.
Visual colour distortion, visual disturbance and blurred vision are listed as common in the EU product information. A dedicated study found mild, temporary blue/green colour-discrimination changes 1 hour after a 100 mg dose, with no effect remaining 2 hours after the dose.
Sudden loss of vision in one eye is listed as rare in the EU product information — between 1 in 10,000 and 1 in 1,000 men. Sildenafil is contraindicated in men who have already lost vision in one eye from NAION.
Contraindicated with nitrate medicines and nitric-oxide donors, because the combination can cause a serious drop in blood pressure.
IN 60 SECONDI
Sul trattamento
Commercializzato anche come Viagra.
Principio attivo: Sildenafil · Dosaggi: 25 / 50 / 100 mg on demand
Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor. It relaxes smooth muscle in the penile blood vessels, facilitating an erection in response to sexual stimulation — it does not cause spontaneous erections or change desire.
It's taken on demand, 30 to 60 minutes before sexual activity; high-fat meals can delay onset. The doctor prescribes the appropriate dose after reviewing your cardiovascular health, current medication and contraindications.
COME AGISCE
By inhibiting the PDE5 enzyme, sildenafil improves blood flow to the penis when there is sexual stimulation. Its effect starts within 30–60 minutes and lasts around 4–6 hours.
During sexual stimulation, nerves and blood vessel linings in the penis release a gas called nitric oxide. Nitric oxide switches on an enzyme, guanylate cyclase, which makes a messenger chemical called cyclic GMP inside the erectile tissue.
Cyclic GMP relaxes the smooth muscle in the corpus cavernosum, the two spongy columns that run the length of the penis. As that muscle relaxes, blood flows in faster than it drains away, and the penis becomes firm.
Sildenafil is a selective blocker of phosphodiesterase type 5, the enzyme that breaks cyclic GMP down. With that enzyme blocked, cyclic GMP lasts longer and the natural response to arousal is stronger. Sildenafil does nothing on its own, so sexual stimulation is still required.
Come aiuta
Taken 30–60 minutes before sex — no daily routine required.
25, 50 or 100 mg — the doctor prescribes what fits your case and tolerance.
Cardiovascular health and interactions are reviewed before any prescription.
Cosa aspettarsi
On demand, before sexual activity. The doctor sets your dose and reviews it with you if the response or tolerance isn't right.
Doses your doctor can prescribe
NELLA VITA QUOTIDIANA
Swallow one tablet whole with a drink of water about one hour before sexual activity. The tablet does not cause an erection by itself, so you still need to feel sexually aroused for it to work.
Never take more than one dose in 24 hours. The usual dose is 50 mg and the maximum licensed dose is 100 mg. In volunteer studies 200 mg did not improve results but did increase side effects.
In a study using a penile measuring device, the median time to an erection firm enough for sex was 25 minutes, with a range of 12 to 37 minutes. Effects can persist four to five hours.
A meal slows absorption. With food, peak blood levels arrive about 60 minutes later and are roughly 29 percent lower, so the tablet may take longer to work. An empty stomach gives the fastest onset.
In healthy volunteers, sildenafil 50 mg did not add to the blood-pressure-lowering effect of alcohol at blood alcohol levels of about 80 mg per decilitre. The NHS still advises not drinking too much while taking it.
Swallow the tablet with water or juice, but not grapefruit juice. Grapefruit juice weakly blocks the same liver enzyme that clears sildenafil, so it can modestly raise the amount of the medicine in your blood.
Some men need to take sildenafil on several separate occasions before they get an erection good enough for sex. If several attempts do not help, or things get worse, tell the doctor rather than raising the dose yourself.
Erection problems often sit alongside high blood pressure, diabetes, high cholesterol or heart disease. The product information advises every man with erectile dysfunction to see a doctor within six months to check for those underlying causes.
Sicurezza prima di tutto
Sildenafil è un farmaco efficace — e, come ogni farmaco, comporta dei rischi. Il medico verifica tutto questo prima di prescrivere. Ecco il quadro onesto, non solo una rassicurazione.
Stop and get urgent medical help if
seek medical help immediately
these need urgent attention, whatever the frequency
Very common
very common (≥1/10)
more than 1 in 10 people
Common
common (≥1/100 to <1/10)
between 1 in 100 and 1 in 10 people
Uncommon
uncommon (≥1/1,000 to <1/100)
between 1 in 1,000 and 1 in 100 people
Rare
rare (≥1/10,000 to <1/1,000)
fewer than 1 in 1,000 people; many of these come from reports made after the medicine was licensed, and the EU label states their true frequency cannot be reliably determined
Prescritto per uomini adulti con disfunzione erettile. Assunto circa 30-60 minuti prima dell'attività sessuale.
CHI NON DEVE ASSUMERLO E CHI RICHIEDE CAUTELA
| FARMACO O SOSTANZA | COSA PUÒ ACCADERE | COSA FA IL MEDICO |
|---|---|---|
| Nitrates and nitric oxide donors (GTN spray, isosorbide, nicorandil, amyl nitrite "poppers") | Sildenafil strongly amplifies their blood-pressure-lowering effect, which can cause collapse. | Contraindicated. The prescriber will not issue sildenafil while these are being used. |
| Riociguat and other guanylate cyclase stimulators | Adds to the blood-pressure fall, with no proven benefit from the combination. | Contraindicated. The prescriber selects a different treatment for erection problems. |
| Alpha-blockers (doxazosin, tamsulosin, alfuzosin) | Can cause dizziness or light-headedness on standing, usually within four hours of the dose. | Stabilise on the alpha-blocker first, then consider starting sildenafil at 25 mg. |
| Ritonavir | Raised sildenafil blood exposure about eleven-fold in a study of healthy volunteers. | Co-administration is not advised; if used at all, never above 25 mg in 48 hours. |
| Other CYP3A4 inhibitors (ketoconazole, itraconazole, erythromycin, cimetidine, saquinavir) | Slow sildenafil clearance; erythromycin raised exposure by 182 percent, cimetidine by 56 percent. | The prescriber considers a 25 mg starting dose. |
| Strong CYP3A4 inducers (rifampicin, bosentan) | Lower sildenafil levels; bosentan cut exposure by about 63 percent in volunteers. | The prescriber may adjust the dose or reconsider the choice of medicine. |
| Sacubitril/valsartan | Blood pressure fell significantly more than with sacubitril/valsartan alone in patients with hypertension. | Caution when starting sildenafil; the prescriber checks blood pressure. |
| Grapefruit juice | A weak inhibitor of gut-wall CYP3A4 that can modestly raise sildenafil blood levels. | Take the tablet with water rather than grapefruit juice. |
EVIDENZE
Sildenafil's licensing evidence comes from the Sildenafil Study Group programme published by Goldstein and colleagues in the New England Journal of Medicine in 1998, together with the fixed-dose studies summarised in the EU product information.
329 men with erectile dysfunction · 12 weeks
Dose-escalation study, sildenafil versus placebo (P<0.001).
Fonte: Goldstein I, et al. Oral sildenafil in the treatment of erectile dysfunction (Sildenafil Study Group)329 men with erectile dysfunction · 12 weeks
Same dose-escalation study, sildenafil versus placebo (P<0.001).
Fonte: Goldstein I, et al. Oral sildenafil in the treatment of erectile dysfunction (Sildenafil Study Group)Men with erectile dysfunction
Fixed-dose studies in the EU product information; 25 percent reported improvement on placebo.
Fonte: Viagra 50 mg film-coated tablets: Summary of Product CharacteristicsMen with erectile dysfunction, dosed while fasting · Single dose
Penile plethysmography (RigiScan) study; range 12 to 37 minutes.
Fonte: Viagra 50 mg film-coated tablets: Summary of Product CharacteristicsMen with erectile dysfunction · Single dose
Separate RigiScan study; sexual stimulation was still needed to produce the response.
Fonte: Viagra 50 mg film-coated tablets: Summary of Product CharacteristicsIn plain terms, roughly seven in ten intercourse attempts worked on sildenafil in the pivotal trial, against roughly two in ten on a dummy tablet. Response rose with dose, from 62 percent of men reporting better erections on 25 mg to 82 percent on 100 mg. These are group averages from selected trial populations, so an individual man may do better, worse, or need a different dose, and the prescriber decides what is appropriate.
ALTERNATIVE
| FARMACO | COME SI ASSUME | OGNI QUANTO | INTERVALLO DI DOSE ABITUALE | INDICAZIONE AUTORIZZATA NELL'UE | EVIDENZA PRINCIPALE |
|---|---|---|---|---|---|
| Tadalafil | Compressa per via orale | Al bisogno, o una volta al giorno | 2.5–20 mg | Treatment of erectile dysfunction in adult men; sexual stimulation is required. | 75% of intercourse attempts succeeded versus 32% on placebo |
| Vardenafil | Compressa per via orale | Al bisogno, massimo una volta al giorno | 5–20 mg | Treatment of erectile dysfunction in adult men; sexual stimulation is required. | 80% achieved penetration on 20 mg versus 49% on placebo |
| Avanafil | Compressa per via orale | Al bisogno, massimo una volta al giorno | 50–200 mg | Treatment of erectile dysfunction in adult men; sexual stimulation is required. | 58% of attempts succeeded on 100 mg versus 28% on placebo |
Non sai quale sia adatto al tuo caso? Il medico esamina la tua storia clinica e te lo dice.
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Across these ten countries sildenafil is normally a prescription-only medicine, with Ireland and Poland the exceptions, where specific sildenafil products are licensed for pharmacist supply without a prescription after a consultation. Where a national source confirmed it, the public health system does not pay for sildenafil used for erectile dysfunction, so the patient carries the cost; the entries left blank are ones we could not confirm from an official national source.
Quanto paghi a Hi-Doctor
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| PAESE | REGIME DI FORNITURA | RIMBORSATO DAL SISTEMA SANITARIO? | FONTE UFFICIALE |
|---|---|---|---|
| Spagna | Medicinale soggetto a prescrizione medica | — | AEMPS CIMA |
| Germania | Medicinale soggetto a prescrizione medica | Excluded from statutory health insurance | PharmNet.Bund AMIce |
|---|---|---|---|
| Francia | Soggetto a prescrizione medica (liste I) | Not reimbursable (non remboursable) | Base de données publique des médicaments |
| Italia | Soggetto a prescrizione medica (non ripetibile) | Not reimbursed (AIFA class C) | AIFA Medicinali |
| Paesi Bassi | Medicinale soggetto a prescrizione medica | Not reimbursed (niet vergoed) | CBG-MEB Geneesmiddeleninformatiebank |
| Portogallo | Soggetto a prescrizione medica (MSRM) | Reimbursement application refused | INFARMED Infomed |
| Belgio | Medicinale soggetto a prescrizione medica | — | FAGG-AFMPS medicines database |
| Irlanda | Soggetto a prescrizione medica; un prodotto da 50 mg in farmacia è fornito senza ricetta | — | HPRA Find a Medicine |
| Austria | Medicinale soggetto a prescrizione medica | Not covered by statutory insurance | BASG Medikamente Info Austria |
| Polonia | Soggetto a prescrizione medica; prodotti in farmacia da 25 mg e 50 mg sono forniti senza ricetta | — | Rejestr Produktów Leczniczych |
PREZZI
35 € per una consultazione di salute sessuale. Un unico pagamento, senza addebiti ricorrenti.
UNA TANTUM
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COSA È INCLUSO
Rimborso completo se una valutazione non viene approvata
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COME DECIDE IL MEDICO
Un medico abilitato nell'UE legge il tuo questionario e risponde in meno di 2 ore in media.
Se il medico decide che non è sicuro prescrivere, il costo della consulenza viene rimborsato per intero.
Il follow-up avviene nella chat privata del tuo account, nel rispetto del GDPR. Niente WhatsApp, niente SMS.
DOMANDE FREQUENTI
ALTRI TRATTAMENTI SALUTE SESSUALE
FONTI
Viagra 50 mg film-coated tablets: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Viagra: EPAR product information (Annex I, Summary of Product Characteristics) — European Medicines Agency, 2026
Viagra: European public assessment report overview — European Medicines Agency, 2026
Goldstein I, et al. Oral sildenafil in the treatment of erectile dysfunction (Sildenafil Study Group) — New England Journal of Medicine, 1998
EAU Guidelines on Sexual and Reproductive Health, 2025 edition (PDE5 inhibitors first-line for erectile dysfunction, strong rating) — European Association of Urology, 2025
Sildenafil (Viagra): NHS medicines A to Z — NHS, 2022
Viagra Connect 50 mg film-coated tablets: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
MHRA reclassifies Viagra Connect tablets to a Pharmacy medicine — Medicines and Healthcare products Regulatory Agency (GOV.UK), 2017
Cialis 20 mg film-coated tablets (tadalafil): Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Vardenafil 20 mg film-coated tablets: Summary of Product Characteristics — electronic medicines compendium (emc), 2025
Spedra 100 mg tablets (avanafil): Summary of Product Characteristics — electronic medicines compendium (emc), 2024
CIMA: sildenafil records, prescription condition "Medicamento sujeto a prescripción médica" — Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), 2026
Sozialgesetzbuch V, §34: medicines excluded from statutory provision, naming erectile dysfunction treatment — Bundesministerium der Justiz (gesetze-im-internet.de), 2026
VIAGRA 50 mg, comprimé pelliculé: liste I, "Prix libre, médicament non remboursable" — Base de données publique des médicaments (ANSM / Ministère de la Santé), 2026
Bollettino d'Informazione sui Farmaci: sildenafil (Viagra) non-repeatable prescription, all packs in fascia C — Agenzia Italiana del Farmaco (AIFA), 2000
Medicijnkosten: sildenafil 50 mg tablets listed as "niet vergoed" — Zorginstituut Nederland, 2026
Relatório de avaliação do pedido de comparticipação: Sildenafil Sandoz, indeferimento 19/07/2010 — INFARMED, I.P., 2010
Viagra Connect 50 mg film-coated tablet: authorised medicine record and pharmacy supply materials — Health Products Regulatory Authority (HPRA), Ireland, 2026
Rejestr Produktów Leczniczych: sildenafil products including Maxigra Go 25 mg and Viagra Connect Max 50 mg — Centrum e-Zdrowia, Poland, 2026
Die Grenzen des Krankenbehandlungsanspruchs am Beispiel der erektilen Dysfunktion (potency medicines on the negative list since April 2004) — Dachverband der österreichischen Sozialversicherungsträger, 2026
Gecommentarieerd Geneesmiddelenrepertorium: sildenafil oral, PDE5 inhibitors for erectile dysfunction — Belgisch Centrum voor Farmacotherapeutische Informatie (BCFI/CBIP), 2026
Revisionato dal team medico di Hi-Doctor · Ultima revisione 2026-07-27 · Prossima revisione prevista il 2027-07-27
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