Posso ottenerlo?
Sì, se un medico ritiene che sia adatto a Lei. Minoxidil è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
Un medico autorizzato dall'UE esamina il Suo caso e, se idoneo, rilascia una prescrizione elettronica valida in qualsiasi farmacia dell'UE ai sensi della direttiva 2011/24/UE.

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IN PAROLE SEMPLICI
Minoxidil è disponibile in due forme molto diverse, e la differenza è importante. Il liquido o la schiuma da applicare sul cuoio capelluto è un medicinale regolarmente autorizzato nei Paesi dell’UE per la perdita di capelli ereditaria maschile. Viene venduto sia con ricetta sia senza, ed è la forma su cui si basano le prove relative alla perdita di capelli riportate sopra. Minoxidil esiste anche in compresse, ma nell’UE queste sono autorizzate solo come medicinale per la pressione sanguigna. Assumere compresse di minoxidil a basso dosaggio per i capelli è un uso fuori indicazione: significa che un medico lo prescrive per un uso diverso da quello autorizzato. I problemi più comuni sono prurito o desquamazione del cuoio capelluto con la forma locale e crescita di peli indesiderati in altre zone. Quest’ultimo problema si è verificato in circa 15 persone su 100 in un ampio studio sulle compresse usate fuori indicazione.
Minoxidil è autorizzato per l’uso nell’UE dal 1 maggio 1988. Un medico abilitato può quindi prescriverlo quando è clinicamente adatto a Lei.
Sì, se un medico ritiene che sia adatto a Lei. Minoxidil è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
I nostri medici esaminano ogni opzione per Crescita dei capelli e consigliano quella più adatta alla Sua storia clinica e ai Suoi obiettivi.
Veda tutte le opzioni per Crescita dei capelliTutti gli studi su Minoxidil sono elencati qui sotto con il numero di partecipanti e l’indicazione se i risultati sono stati sottoposti a revisione paritaria o provengono da un annuncio dell’azienda.
Vada agli studiEVIDENZE VERIFICATE
CHE COS’È
Applied to the scalp it widens small blood vessels and appears to keep hair follicles in their growing phase for longer, although exactly how it acts on hair is still not fully understood.
FASE DI SVILUPPO
Ogni identificativo NCT rimanda al record ClinicalTrials.gov. Una comunicazione dei risultati non equivale a una pubblicazione sottoposta a revisione paritaria.
| STUDIO / NCT | POPOLAZIONE | PARTECIPANTI | STATO | RISULTATO / COMPLETAMENTO |
|---|---|---|---|---|
| 5% vs 2% topical minoxidil solution vs placebo in men (48-week, double-blind, multicentre) | Men aged 18-49 with vertex androgenetic alopecia | 393 | Con risultati | 2002-09-01 |
| Oral minoxidil 5 mg vs topical minoxidil 5% (double-blind randomised clinical trial, Brazil; registry RBR-252w9r) | Men aged 18-55 with androgenetic alopecia; 68 of 90 randomised completed | 90 | Con risultati | 2024-04-10 |
I risultati sono separati per fonte e grado di evidenza, così i dati scientifici non vengono confusi con gli annunci del produttore.
| DOSE O GRUPPO | VARIAZIONE MEDIA DEL PESO | SETTIMANE |
|---|---|---|
| 5% topical solution, twice daily | +18.6 non-vellus hairs/cm2 from baseline | 48 |
| 2% topical solution, twice daily | +12.7 non-vellus hairs/cm2 from baseline | 48 |
| placebo (vehicle), twice daily | +3.9 non-vellus hairs/cm2 from baseline | 48 |
The trial ran for 48 weeks in men aged 18-49 with vertex-pattern loss, so it does not establish results beyond one year or in other patterns of hair loss.
Ultima revisione 2026-07-27
SEGNALI DI SICUREZZA IDENTIFICATI
Itching, dermatitis, acneiform dermatitis and rash are listed as common in the EU product information for topical minoxidil. Application-site reactions can occasionally be more severe and include peeling, blistering, bleeding or ulceration.
Listed as common in the EU product information for topical minoxidil, including facial hair growth in women.
Headache and dyspnoea are listed as common; dizziness, nausea and peripheral oedema as uncommon; palpitations, tachycardia and chest pain as rare; low blood pressure and allergic reactions including angioedema at a frequency that is not known.
Temporary hair loss is listed in the EU product information at a frequency that is not known.
In a 24-week randomised trial of oral minoxidil 5 mg vs topical minoxidil 5% (n=45 per arm), hypertrichosis occurred in 22/45 (49%) on the oral drug vs 11/45 (25%) on topical (P=.02) and headache in 6/45 (14%) vs 1/45 (2%) (P=.046); scalp eczema was more frequent with topical, 7/45 (16%) vs 1/45 (2%).
In a retrospective multicentre study of 1,404 patients treated for at least 3 months, the most frequent adverse effect was hypertrichosis (15.1%, causing withdrawal in 0.5%). Systemic effects were lightheadedness 1.7%, fluid retention 1.3%, tachycardia 0.9%, headache 0.4%, periorbital oedema 0.3% and insomnia 0.2%, leading to discontinuation in 1.2% of patients.
EU-authorised minoxidil tablets are indicated only for severe resistant high blood pressure and their product information states they must never be used alone or as initial therapy, always alongside a beta-blocker and a diuretic. None of that licensed dosing framework applies to the low doses used off-label for hair loss.
IN 60 SECONDI
Sul trattamento
Commercializzato anche come Oral minoxidil, Regaine, Rogaine, Topical minoxidil.
Principio attivo: Minoxidil · Dosaggi: 5% topical · 2.5–5 mg oral
Minoxidil prolongs the anagen (growth) phase of the hair follicle and increases hair diameter. Topical is the standard in mild-to-moderate androgenetic alopecia; low-dose oral — off-label, under medical supervision — is an alternative when adherence to topical is poor or the response is insufficient.
It's frequently combined with a 5-alpha-reductase inhibitor: minoxidil stimulates the follicle while finasteride or dutasteride blocks the hormonal cause. The doctor decides the form and the combination based on your history and pattern of loss.
COME AGISCE
Minoxidil extends the follicle's growth phase and increases hair diameter, improving density where follicles are still active. Each form — topical or low-dose oral — has its own side-effect profile, which the doctor reviews with you.
Your body converts minoxidil into minoxidil sulfate, its active form. That form opens ATP-sensitive potassium channels in the smooth muscle lining small blood vessels. Potassium flows out of the cell, the muscle relaxes, and the vessel widens. This is the same action that lowers blood pressure in tablet form.
Wider vessels mean more microcirculation reaching each hair follicle. Minoxidil also raises vascular endothelial growth factor, a signal the manufacturer's product information says is probably responsible for the extra openings in nearby capillaries. Those openings feed a follicle while it is actively growing and burning energy.
Follicles then stay longer in anagen, the active growing phase, leave the resting phase sooner, and produce a thicker hair shaft. How minoxidil produces this effect in hair is still not fully established. The product information describes what happens rather than one proven pathway.
Come aiuta
Prolongs the growth phase and thickens the hair shaft.
Topical solution as the standard; low-dose oral when topical doesn't fit.
Often combined with finasteride or dutasteride to also block the hormonal cause.
Cosa aspettarsi
Topical is applied twice daily to thinning areas; the oral form is a once-daily low-dose tablet. Your doctor prescribes the form most appropriate for you.
Forms your doctor can prescribe
NELLA VITA QUOTIDIANA
Hair and scalp must be thoroughly dry before you apply minoxidil. Damp skin absorbs more of it than intended, which raises the chance of dizziness, a faster heartbeat and other whole-body effects.
One dose is 1 ml of solution, which is six presses of the pump, or 1 g of foam, roughly half a cap. Do not exceed 2 ml or 2 g in any 24 hours.
Apply to the centre of the thinning area on the scalp, then spread outwards with your fingertips. It goes on the scalp only, never on other parts of the body.
Wash your hands thoroughly straight after applying. Minoxidil carried from hands, pillows or towels onto the face, or onto another person, can grow unwanted hair there, and that is a commonly reported effect.
Give the scalp time to dry before styling, putting on a hat or going to bed. Do not cover a treated scalp with dressings or other occlusive coverings, which push more of the drug through the skin.
The 5% products for men are applied twice daily, morning and evening. Missed applications reduce the effect, because the benefit depends on continuous exposure rather than on building up a reserve in the body.
If a doctor prescribes minoxidil tablets for hair loss, that is an off-label use of a blood-pressure medicine. Take the exact dose prescribed, at the same time each day, and never adjust it yourself.
Minoxidil holds hair only while you use it. Regrown hair can disappear three to four months after stopping, and normal balding then resumes. Tell the prescriber before you stop rather than stopping quietly.
Sicurezza prima di tutto
Minoxidil è un farmaco efficace — e, come ogni farmaco, comporta dei rischi. Il medico verifica tutto questo prima di prescrivere. Ecco il quadro onesto, non solo una rassicurazione.
Stop and get urgent medical help if
seek medical help immediately
these need urgent attention, whatever the frequency
Very common
very common (≥1/10)
more than 1 in 10 people
Common
common (≥1/100 to <1/10)
between 1 in 100 and 1 in 10 people
Uncommon
uncommon (≥1/1,000 to <1/100)
between 1 in 1,000 and 1 in 100 people
Rare
rare (≥1/10,000 to <1/1,000)
between 1 in 10,000 and 1 in 1,000 people
Reported, frequency not known
frequency not known
reported after the medicine was licensed; how often is not established
Adulti con alopecia androgenetica o telogen effluvium.
CHI NON DEVE ASSUMERLO E CHI RICHIEDE CAUTELA
| FARMACO O SOSTANZA | COSA PUÒ ACCADERE | COSA FA IL MEDICO |
|---|---|---|
| Other blood-pressure medicines | Blood-pressure lowering adds up, so pressure can fall further than intended. | The prescriber reviews every blood-pressure medicine before considering oral minoxidil. |
| Guanethidine or betanidine | Reported to cause excessive blood-pressure drops and dizziness on standing. | Guanethidine is stopped before oral minoxidil is started. |
| Other peripheral vasodilators | May add to dizziness on standing, a theoretical risk even with topical minoxidil. | The prescriber checks for overlapping vasodilators and reviews symptoms at follow-up. |
| Other medicated scalp treatments | Should not be applied to the scalp at the same time as minoxidil. | The prescriber sequences scalp treatments instead of layering them together. |
| Topical corticosteroids, tretinoin, dithranol or petrolatum | Alter the skin barrier and can increase how much minoxidil is absorbed. | Kept off the treated scalp unless a doctor has specifically agreed to it. |
| Anti-inflammatory painkillers and calcium channel blockers | May add to the fluid retention and ankle swelling seen with oral minoxidil. | The prescriber watches for swelling and reviews whether the combination continues. |
EVIDENZE
Most of what is known about minoxidil comes from the manufacturer's phase 3 topical trials and, for the oral route, a 1,404-patient multicentre safety study and a 2,933-patient meta-analysis.
Men with androgenetic alopecia · 16 weeks
Phase 3 trial; the placebo group gained 4.3 hairs per cm².
Fonte: Regaine for Men Extra Strength Scalp Foam 5% w/w: Summary of Product CharacteristicsMen with androgenetic alopecia · 48 weeks
Manufacturer's trial; 23% reported the same on the vehicle alone, so the comparison is not against no treatment.
Fonte: Regaine for Men Extra Strength Scalp Solution 5% w/v: Summary of Product Characteristics2,933 patients across 27 studies, taking 0.25 to 5 mg daily
95% confidence interval 22 to 49%.
Fonte: Efficacy and safety of oral minoxidil in the treatment of alopecia: a meta-analysis and systematic review1,404 patients in a multicentre series
Unwanted body hair, which led only 0.5% of them to stop treatment.
Fonte: Safety of low-dose oral minoxidil for hair loss: a multicenter study of 1404 patients1,404 patients in the same multicentre series
Lightheadedness affected 1.7%, fluid retention 1.3% and tachycardia 0.9%.
Fonte: Safety of low-dose oral minoxidil for hair loss: a multicenter study of 1404 patientsThese figures are averages across whole trial groups, not a forecast for any one person, and within the same trials some people gained far more hair and some gained none. Hair counts are taken from a small marked patch of scalp, so a gain of around 21 hairs per cm² reads as visible thickening rather than a restored hairline. The oral numbers come mostly from clinics reporting their own patients rather than from large randomised trials, so they carry more uncertainty than the topical ones.
ALTERNATIVE
| FARMACO | COME SI ASSUME | OGNI QUANTO | INTERVALLO DI DOSE ABITUALE | INDICAZIONE AUTORIZZATA NELL'UE | EVIDENZA PRINCIPALE |
|---|---|---|---|---|---|
| Minoxidil | Soluzione o schiuma topica; compressa orale è off-label | Due volte al giorno per via topica; una volta al giorno se orale | 2% or 5% topical, max 2 ml or 2 g daily; oral 0.25 to 5 mg | Androgenetic alopecia in adults; the tablet is licensed only for severe high blood pressure | Phase 3 foam trial: +21.0 hairs/cm² at week 16 vs +4.3 |
| Finasteride | Compressa orale | Una volta al giorno | 1 mg daily | Male pattern hair loss in men, to increase hair growth and prevent further loss | 5-year trial: 48% of men rated improved on standardised photographs |
| Dutasteride | Capsula molle orale | Una volta al giorno | 0.5 mg daily | Licensed in the EU for benign prostatic hyperplasia; hair-loss use is off-label | 24-week trial: higher hair count than finasteride 1 mg (P = .003) |
Non sai quale sia adatto al tuo caso? Il medico esamina la tua storia clinica e te lo dice.
Inizia consulto · 15 €/meseACCESSO E COSTI
This shows whether you can obtain minoxidil without a prescription in each country, and who pays. Topical minoxidil is sold through pharmacies without a prescription across these markets, while minoxidil tablets are prescription-only everywhere and are licensed for high blood pressure, not for hair loss.
Quanto paghi a Hi-Doctor
15 €/mese (fatturati 45 € ogni 90 giorni)
Risponda ad alcune domande e un medico autorizzato dall'UE esaminerà il Suo caso in meno di 2 ore in media. Rimborso completo se non fa per Lei.
Quanto addebita la farmacia
Hi-Doctor non vende, non detiene e non dispensa farmaci e non ne stabilisce il prezzo. Il farmaco si paga separatamente in farmacia e l'importo dipende dal paese, dalla confezione, dalla disponibilità di un generico e dalla rimborsabilità. La banca dati ufficiale collegata nella tabella pubblica il prezzo autorizzato in vigore.
| PAESE | REGIME DI FORNITURA | RIMBORSATO DAL SISTEMA SANITARIO? | FONTE UFFICIALE |
|---|---|---|---|
| Spagna | Topico: in farmacia, senza ricetta. Orale: soggetto a prescrizione medica (off-label per il capello) | Not reimbursed for hair loss | AEMPS CIMA |
| Germania | Topical: pharmacy-only, no prescription. Oral: prescription-only (off-label for hair) | Not reimbursed for hair loss | PharmNet.Bund AMIce |
|---|---|---|---|
| Francia | Topico: non soggetto a prescrizione. Orale: Liste I, soggetto a prescrizione medica (off-label per il capello) | Topical not reimbursable for hair loss | Base de données publique des médicaments |
| Italia | Topico: in farmacia, senza ricetta (classe C). Orale: soggetto a prescrizione medica (off-label per il capello) | Not reimbursed for hair loss | AIFA Medicinali |
| Paesi Bassi | Topico: in farmacia, senza ricetta. Orale: soggetto a prescrizione medica (off-label per il capello) | Not reimbursed for hair loss | CBG-MEB Geneesmiddeleninformatiebank |
| Portogallo | Topical: MNSRM, no prescription. Oral: prescription-only (off-label for hair) | Not reimbursed for hair loss | INFARMED Infomed |
| Belgio | Topico: senza ricetta da agosto 2024. Orale: non registrato in Belgio | Not reimbursed for hair loss | FAGG-AFMPS medicines database |
| Irlanda | Topico: fornito solo in farmacia. Orale: soggetto a prescrizione medica (off-label per il capello) | Not reimbursed for hair loss | HPRA Find a Medicine |
| Austria | Topico: in farmacia, senza ricetta. Orale: soggetto a prescrizione medica (off-label per il capello) | Not reimbursed for hair loss | BASG Medikamente Info Austria |
| Polonia | Topico: disponibile in farmacia. Orale: nessuna compressa di minoxidil nel registro nazionale | Not reimbursed for hair loss | Rejestr Produktów Leczniczych |
PREZZI
25 €/mese per il controllo del peso o 15 €/mese (fatturati 45 € ogni 90 giorni) per la crescita dei capelli. Per la salute sessuale è disponibile una consultazione una tantum da 35 €.
PIANO CONTINUATIVO
15 €/mese
Fatturati 45 € ogni 90 giorni · annulli quando vuoi
Per un trattamento continuativo e rinnovi valutati dal Suo medico.
Il nostro prezzo mensile più basso
Rimborso completo se una valutazione non viene approvata
COSA È INCLUSO
Rimborso completo se una valutazione non viene approvata
Se una valutazione non viene approvata, rimborsiamo la quota di 45 € di quel periodo e annulliamo il piano.
Nota: Il farmaco, se prescritto dal medico, viene pagato separatamente in farmacia al prezzo stabilito. Hi-Doctor non vende farmaci.
COME DECIDE IL MEDICO
Un medico abilitato nell'UE legge il tuo questionario e risponde in meno di 2 ore in media.
Se il medico decide che non è sicuro prescrivere, il costo della consulenza viene rimborsato per intero.
Il follow-up avviene nella chat privata del tuo account, nel rispetto del GDPR. Niente WhatsApp, niente SMS.
DOMANDE FREQUENTI
ALTRI TRATTAMENTI CRESCITA DEI CAPELLI
FONTI
Regaine for Men Extra Strength Scalp Solution 5% w/v: Summary of Product Characteristics — electronic medicines compendium (emc), 2024
Regaine for Men Extra Strength Scalp Foam 5% w/w: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Regaine for Women Regular Strength 2% w/v: Summary of Product Characteristics — electronic medicines compendium (emc), 2024
Loniten 5 mg Tablets (oral minoxidil): Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Hair loss: treatments and what the NHS provides — NHS, 2026
Oral minoxidil treatment for hair loss: a review of efficacy and safety — Journal of the American Academy of Dermatology, 2021
Safety of low-dose oral minoxidil for hair loss: a multicenter study of 1404 patients — Journal of the American Academy of Dermatology, 2021
Summation and recommendations for the safe and effective use of topical and oral minoxidil — Journal of the American Academy of Dermatology, 2025
Efficacy and safety of oral minoxidil in the treatment of alopecia: a meta-analysis and systematic review — Frontiers in Pharmacology, 2025
Characterization and management of adverse events of low-dose oral minoxidil treatment for alopecia — Journal of Clinical Medicine, 2025
Propecia 1 mg film-coated tablets (finasteride): Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Avodart 0.5 mg soft capsules (dutasteride): Summary of Product Characteristics — electronic medicines compendium (emc), 2024
Randomized study of dutasteride versus placebo and finasteride in male androgenetic alopecia — Journal of the American Academy of Dermatology, 2014
CIMA: Centro de Informacion de Medicamentos, minoxidil product records — AEMPS (Spanish Agency of Medicines and Medical Devices), 2026
Base de donnees publique des medicaments: Alostil 5% and Lonoten 5 mg records — ANSM / Ministere de la Sante (France), 2026
Geneesmiddeleninformatiebank: Lonnoten 10 mg tablets (RVG 08426) and topical minoxidil records — College ter Beoordeling van Geneesmiddelen (Netherlands), 2026
Rejestr Produktow Leczniczych: minoxidil (Minoxidilum) product records — Ministry of Health (Poland), 2026
Regaine 5% Schaum fuer Maenner: Fachinformation (Austrian SmPC) — BASG / Medikamente Info Austria, 2026
Regaine for Men Extra Strength Scalp Foam 5% w/w: Irish SmPC, legal category supply through pharmacy only — HPRA / medicines.ie (Ireland), 2025
INFOMED: base de dados de medicamentos de uso humano — INFARMED (Portugal), 2026
Gecommentarieerd Geneesmiddelenrepertorium: minoxidil product records — BCFI / CBIP (Belgium), 2026
Revisionato dal team medico di Hi-Doctor · Ultima revisione 2026-07-27 · Prossima revisione prevista il 2027-07-27
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