Posso ottenerlo?
Sì, se un medico ritiene che sia adatto a Lei. Tadalafil 10/20mg è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
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IN PAROLE SEMPLICI
Tadalafil è una compressa con obbligo di ricetta per la disfunzione erettile, autorizzata in tutta l’UE dal 2002. Come sildenafil, rilassa i vasi sanguigni del pene affinché il sangue possa affluire, e la stimolazione sessuale è comunque necessaria perché funzioni. La sua caratteristica distintiva è la durata dell’effetto: le informazioni sul prodotto dell’UE indicano un effetto misurabile fino a 36 ore dopo una dose. Esiste anche come compressa a basso dosaggio da assumere una volta al giorno invece che prima del rapporto sessuale e non può essere combinato con medicinali nitrati per il cuore.
Tadalafil 10/20mg è autorizzato per l’uso nell’UE dal 12 novembre 2002. Un medico abilitato può quindi prescriverlo quando è clinicamente adatto a Lei.
Sì, se un medico ritiene che sia adatto a Lei. Tadalafil 10/20mg è autorizzato nell’UE e può essere prescritto dopo una valutazione medica.
I nostri medici esaminano ogni opzione per Salute sessuale e consigliano quella più adatta alla Sua storia clinica e ai Suoi obiettivi.
Veda tutte le opzioni per Salute sessualeTutti gli studi su Tadalafil 10/20mg sono elencati qui sotto con il numero di partecipanti e l’indicazione se i risultati sono stati sottoposti a revisione paritaria o provengono da un annuncio dell’azienda.
Vada agli studiEVIDENZE VERIFICATE
CHE COS’È
Tadalafil blocks the PDE5 enzyme that normally ends an erection, keeping the blood vessels in the penis relaxed so blood can flow in when a man is sexually aroused.
FASE DI SVILUPPO
Ogni identificativo NCT rimanda al record ClinicalTrials.gov. Una comunicazione dei risultati non equivale a una pubblicazione sottoposta a revisione paritaria.
| STUDIO / NCT | POPOLAZIONE | PARTECIPANTI | STATO | RISULTATO / COMPLETAMENTO |
|---|---|---|---|---|
| Integrated analysis of five randomised, double-blind, placebo-controlled 12-week trials | Men aged 22-82 (mean 59) with mild to severe erectile dysfunction of various causes | 1,112 | Con risultati | 2002-10-01 |
| Three at-home period-of-responsiveness studies | Men with erectile dysfunction | 1,054 | Con risultati | — |
I risultati sono separati per fonte e grado di evidenza, così i dati scientifici non vengono confusi con gli annunci del produttore.
| DOSE O GRUPPO | VARIAZIONE MEDIA DEL PESO | SETTIMANE |
|---|---|---|
| 20 mg | Mean improvement of 7.9 points from baseline on the IIEF erectile function domain (p<0.001 vs placebo) | 12 |
| 20 mg | 75% of intercourse attempts completed (SEP question 3), p<0.001 vs placebo | 12 |
| 20 mg | 81% reported improved erections vs 35% on placebo (Global Assessment Question), p<0.001 | 12 |
This pooled five 12-week manufacturer-run trials, and the 7.9-point IIEF change is the within-group change from baseline rather than the difference from placebo.
SEGNALI DI SICUREZZA IDENTIFICATI
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men. Frequency rises with higher doses. With once-daily dosing, most headaches occur in the first 10 to 30 days of treatment.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men. Named alongside headache, dyspepsia and myalgia as one of the most frequently reported reactions, with frequency rising at higher doses.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men, with frequency rising at higher doses.
Listed as common in the EU product information — between 1 in 100 and 1 in 10 men.
Both listed as common in the EU product information — between 1 in 100 and 1 in 10 men.
Contraindicated in men who have lost vision in one eye because of NAION, whether or not the episode was linked to a PDE5 inhibitor.
Contraindicated with nitrate medicines and with guanylate cyclase stimulators, and after a recent heart attack (within 3 months) or stroke (within 6 months).
IN 60 SECONDI
DATI DEL PRODOTTO
Sul trattamento
Cialis contiene il principio attivo tadalafil.
Principio attivo: Tadalafil · Dosaggi: 10 / 20 mg on demand · 5 mg daily
Tadalafil is a PDE5 inhibitor whose long half-life sets it apart — up to 36 hours of therapeutic window. That allows spontaneity, and a low-dose daily regimen is available for continuous use when clinically appropriate.
It also suits people who respond better to sustained action, and it's considered in cases with lower urinary tract symptoms (BPH), where tadalafil is indicated. The doctor weighs the on-demand versus daily approach with you.
COME AGISCE
Like other PDE5 inhibitors it improves blood flow in response to stimulation — but its effect persists far longer. The on-demand dose acts in 30–60 minutes; the low daily dose reaches a steady effect in a few days.
Sexual stimulation is what starts the process. Nerves and the lining of the blood vessels in the penis release nitric oxide, which triggers a messenger chemical called cyclic guanosine monophosphate, usually shortened to cGMP. Without arousal, tadalafil does nothing at all.
Tadalafil is a selective, reversible blocker of an enzyme called phosphodiesterase type 5, or PDE5, whose normal job is to break cGMP back down. With PDE5 blocked, cGMP builds up in the erectile tissue instead of being cleared away as fast as it appears.
Higher cGMP relaxes the smooth muscle in the arteries of the corpus cavernosum, so blood flows into the penis and an erection can form. The same relaxation happens in the prostate and bladder, which is why a daily dose can also ease urinary symptoms.
Come aiuta
One on-demand dose covers a much longer period than other PDE5s.
A low daily dose allows sexual activity without planning, when appropriate.
Cardiovascular health and interactions are reviewed before any prescription.
Cosa aspettarsi
On demand or as a low daily dose — your doctor recommends the regimen that fits your frequency and preferences.
Doses your doctor can prescribe
NELLA VITA QUOTIDIANA
There are two routes. On demand means one tablet before sex. Once daily means a small tablet every day, so dosing and sex are no longer linked. Your prescriber chooses with you, mainly based on how often sex is expected.
On the on-demand route, swallow the tablet whole at least 30 minutes before sexual activity. Peak blood levels are reached at around two hours. Never take more than one dose in any 24-hour period.
Tadalafil can be taken with or without food, because the rate and extent of absorption are not influenced by meals. Dosing in the morning versus the evening also makes no clinically relevant difference to absorption.
The tablet does not produce an erection on its own. Sexual stimulation is required for it to work. If nothing happens without arousal, that is expected behaviour rather than a sign the dose is too low.
On the once-daily route, take the tablet at roughly the same time every day. Steady levels in the blood are reached within five days of daily dosing, so judge the effect after that point, not on day one.
Tadalafil did not increase the average blood-pressure drop caused by alcohol in studies, but some people had postural dizziness and a drop in blood pressure on standing. Heavy drinking also makes erections harder to achieve.
Grapefruit juice and medicines such as ritonavir, ketoconazole, itraconazole, erythromycin and clarithromycin raise tadalafil levels. Rifampicin, phenytoin and carbamazepine lower them. Include recreational drugs, especially poppers.
Whether continued daily use still suits you should be reassessed periodically. Report side effects, and tell any doctor treating you for chest pain that you take tadalafil, before nitrates are given.
Sicurezza prima di tutto
Tadalafil 10/20mg è un farmaco efficace — e, come ogni farmaco, comporta dei rischi. Il medico verifica tutto questo prima di prescrivere. Ecco il quadro onesto, non solo una rassicurazione.
Stop and get urgent medical help if
seek medical help immediately
these need urgent attention, whatever the frequency
Common
common (≥1/100 to <1/10)
somewhere between 1 in 100 and 1 in 10 people
Uncommon
uncommon (≥1/1,000 to <1/100)
somewhere between 1 in 1,000 and 1 in 100 people
Rare
rare (≥1/10,000 to <1/1,000)
somewhere between 1 in 10,000 and 1 in 1,000 people
Prescritto per uomini adulti con disfunzione erettile in due regimi.
CHI NON DEVE ASSUMERLO E CHI RICHIEDE CAUTELA
| FARMACO O SOSTANZA | COSA PUÒ ACCADERE | COSA FA IL MEDICO |
|---|---|---|
| Nitrates (e.g. GTN spray, isosorbide) | Tadalafil amplifies the blood-pressure drop from nitrates, which can be large and unpredictable | Absolute bar to prescribing; at least 48 hours must pass before emergency nitrates |
| Riociguat and other guanylate cyclase stimulators | Adds to the blood-pressure-lowering effect and can cause symptomatic low blood pressure | Contraindicated, so the prescriber selects a different treatment entirely |
| Doxazosin (an alpha-blocker) | Significantly increases doxazosin's blood-pressure drop for at least twelve hours, sometimes causing fainting | Combination not recommended; prescriber may change the alpha-blocker or avoid tadalafil |
| Other alpha-blockers (alfuzosin, tamsulosin) | Both are blood-vessel relaxants, so blood pressure can fall further, especially in older men | Start at the minimum dose and adjust gradually, with extra caution in the elderly |
| Ritonavir, ketoconazole, itraconazole, erythromycin, grapefruit juice | Block the CYP3A4 enzyme; ketoconazole 400 mg daily quadrupled tadalafil exposure in a study | Prescribe with caution, and a lower tadalafil dose may be chosen |
| Rifampicin, phenytoin, carbamazepine, phenobarbital | Speed up tadalafil breakdown; rifampicin cut tadalafil exposure by 88% in a study | Expect a weaker effect; the prescriber reviews whether tadalafil still suits you |
| Blood-pressure medicines (ACE inhibitors, beta-blockers, diuretics, calcium blockers) | A small extra fall in blood pressure, generally minor and not likely to be clinically relevant | Usually allowed, with advice about dizziness and a possible review of doses |
| Other erectile dysfunction treatments | Combining tadalafil with other ED treatments has not been studied for safety or effectiveness | Do not combine; the prescriber keeps you on one treatment at a time |
EVIDENZE
In the tadalafil registration trials, both the on-demand and the once-daily regimens improved erectile function and the share of successful intercourse attempts compared with placebo, and one dedicated trial found the effect was still measurable 36 hours after a single dose.
1,112 men with erectile dysfunction · 12 weeks
Integrated analysis of five placebo-controlled trials, p<0.001 versus placebo
Fonte: Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses1,112 men with erectile dysfunction · 12 weeks
Sexual Encounter Profile question 3 in the same integrated analysis, p<0.001 versus placebo
Fonte: Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses348 men with erectile dysfunction in Europe and the United States · Single dose, assessed at 36 hours
Randomised to tadalafil 20 mg or placebo, p<0.001
Fonte: Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hours after dosing: a randomized controlled trialMen with erectile dysfunction · 12 weeks
Dose-response study; 35% of men on placebo also reported improved erections
Fonte: EAU Guidelines on Sexual and Reproductive Health, limited update March 2025217 treatment-naive men with erectile dysfunction
Randomised to tadalafil 5 mg daily or placebo, mean per-subject proportion
Fonte: Cialis (tadalafil): Summary of Product Characteristics, Annex IThese figures are group averages, not promises. In the trials a typical man on tadalafil completed a clear majority of intercourse attempts, while a meaningful share of men on dummy tablets also improved, which is why the comparison against placebo matters more than the headline number. Your own response may be better or worse than the average, and the only way to know is to try the dose your prescriber recommends and report back.
ALTERNATIVE
| FARMACO | COME SI ASSUME | OGNI QUANTO | INTERVALLO DI DOSE ABITUALE | INDICAZIONE AUTORIZZATA NELL'UE | EVIDENZA PRINCIPALE |
|---|---|---|---|---|---|
| Sildenafil | Compressa per via orale | Al bisogno, massimo una volta al giorno | 25–100 mg | Erectile dysfunction in adult men; sexual stimulation is required | Dose-response study: improved erections 56%, 77%, 84% vs 25% placebo |
| Vardenafil | Compressa per via orale | Al bisogno, massimo una volta al giorno | 5–20 mg | Erectile dysfunction in adult men; sexual stimulation is required | Dose-response study: improved erections 66%, 76%, 80% vs 30% placebo |
| Avanafil | Compressa per via orale | Al bisogno, massimo una volta al giorno | 50–200 mg | Erectile dysfunction in adult men; sexual stimulation is required | Successful attempts 47%, 58%, 59% vs 28% placebo across the three doses |
Non sai quale sia adatto al tuo caso? Il medico esamina la tua storia clinica e te lo dice.
Inizia consulto · 35 €ACCESSO E COSTI
This describes how tadalafil is legally supplied in each country and whether the public health system pays, not what any consultation costs. Rows say "See national criteria" where the reimbursement position could not be confirmed from an official national source, rather than guessing.
Quanto paghi a Hi-Doctor
35 € una tantum
Risponda ad alcune domande e un medico autorizzato dall'UE esaminerà il Suo caso in meno di 2 ore in media. Rimborso completo se non fa per Lei.
Quanto addebita la farmacia
Hi-Doctor non vende, non detiene e non dispensa farmaci e non ne stabilisce il prezzo. Il farmaco si paga separatamente in farmacia e l'importo dipende dal paese, dalla confezione, dalla disponibilità di un generico e dalla rimborsabilità. La banca dati ufficiale collegata nella tabella pubblica il prezzo autorizzato in vigore.
| PAESE | REGIME DI FORNITURA | RIMBORSATO DAL SISTEMA SANITARIO? | FONTE UFFICIALE |
|---|---|---|---|
| Spagna | Medicinale soggetto a prescrizione medica | See national criteria | AEMPS CIMA |
| Germania | Medicinale soggetto a prescrizione medica | Excluded from statutory health insurance | PharmNet.Bund AMIce |
|---|---|---|---|
| Francia | Soggetto a prescrizione medica (liste I) | Not reimbursable | Base de données publique des médicaments |
| Italia | Soggetto a prescrizione medica (ricetta ripetibile) | Restricted — AIFA Nota 75 criteria only | AIFA Medicinali |
| Paesi Bassi | Medicinale soggetto a prescrizione medica | Not reimbursed for erectile dysfunction | CBG-MEB Geneesmiddeleninformatiebank |
| Portogallo | Soggetto a prescrizione medica (MSRM) | Reimbursement rate 0% | INFARMED Infomed |
| Belgio | Medicinale soggetto a prescrizione medica | See national criteria | FAGG-AFMPS medicines database |
| Irlanda | Soggetto a prescrizione medica, più un prodotto in farmacia da 10 mg | See national criteria | HPRA Find a Medicine |
| Austria | Soggetto a prescrizione medica (Rp) | See national criteria | BASG Medikamente Info Austria |
| Polonia | Soggetto a prescrizione medica, più un prodotto da 10 mg venduto OTC | See national criteria | Rejestr Produktów Leczniczych |
PREZZI
35 € per una consultazione di salute sessuale. Un unico pagamento, senza addebiti ricorrenti.
UNA TANTUM
35 € una tantum
Un consulto, un medico, una decisione.
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COSA È INCLUSO
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COME DECIDE IL MEDICO
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Se il medico decide che non è sicuro prescrivere, il costo della consulenza viene rimborsato per intero.
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DOMANDE FREQUENTI
ALTRI TRATTAMENTI SALUTE SESSUALE
FONTI
Cialis (tadalafil): Summary of Product Characteristics, Annex I — European Medicines Agency, 2025
Cialis: EPAR medicine overview — European Medicines Agency, 2002
Cialis 20 mg film-coated tablets: Summary of Product Characteristics — electronic medicines compendium (emc), 2026
Tadalafil: NHS medicines A to Z — National Health Service (UK), 2026
Efficacy and safety of tadalafil for the treatment of erectile dysfunction: results of integrated analyses — The Journal of Urology 168(4 Pt 1):1332-6, 2002
Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hours after dosing: a randomized controlled trial — Urology 62(1):121-5, 2003
EAU Guidelines on Sexual and Reproductive Health, limited update March 2025 — European Association of Urology, 2025
Viagra (sildenafil): Summary of Product Characteristics, Annex I — European Medicines Agency, 2025
Levitra (vardenafil): Summary of Product Characteristics, Annex I — European Medicines Agency, 2024
Spedra (avanafil): Summary of Product Characteristics, Annex I — European Medicines Agency, 2025
Tadalafilo: authorised medicines register (99 entries, prescription-only) — AEMPS CIMA, Spain, 2026
CIALIS 20 mg comprimé pelliculé: liste I, non remboursable, prix libre — Base de données publique des médicaments, France, 2026
§ 34 SGB V: medicines excluded from statutory health insurance, including erectile dysfunction — Bundesministerium der Justiz, Germany, 2026
Nota 75: PDE5 inhibitor reimbursement limited to neurogenic erectile dysfunction — AIFA, Gazzetta Ufficiale della Repubblica Italiana n. 7, 2017
Tadalafil: not reimbursed by basic health insurance — Medicijnkosten.nl, Zorginstituut Nederland, 2026
Lista de medicamentos genéricos disponíveis no mercado: tadalafil, taxa de comparticipação 0% — INFARMED, Portugal, 2026
Public assessment report: Cialis for men 10 mg film-coated tablets, a non-prescription tadalafil medicine — Health Products Regulatory Authority, Ireland, 2024
Tadalafil Mensil 10 mg: availability category OTC, medicine supplied without a doctor's prescription — Rejestr Produktów Leczniczych, Poland, 2026
Tadalafil 5 mg oral tablet: Cialis and seven generics listed under erectile dysfunction — CBIP/BCFI Répertoire Commenté des Médicaments, Belgium, 2026
Arzneispezialitätenregister: authorised medicines register — BASG, Austria, 2026
Revisionato dal team medico di Hi-Doctor · Ultima revisione 2026-07-27 · Prossima revisione prevista il 2027-07-27
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