Skip to content
Hi-Doctor
← Back to consultationInternal patient-safety page

MEDICATION SAFETY

Tirzepatide safety summary

  • INN
  • tirzepatide
  • dual GIP / GLP-1 receptor agonist
  • once-weekly subcutaneous injection
  • brand: Mounjaro

Tirzepatide is a dual GIP / GLP-1 receptor agonist that reduces appetite and slows gastric emptying. The dual mechanism delivers stronger weight reduction than single-pathway GLP-1 medicines in head-to-head trials. It is prescribed for chronic weight management alongside a reduced-calorie diet and increased physical activity.

Adults with obesity (BMI ≥30) or with overweight (BMI ≥27) plus at least one weight-related condition.

  • Once-weekly self-injection in the thigh, abdomen or upper arm.
  • Dose is escalated step-wise (2.5 mg → 5 → 7.5 → 10 → 12.5 → 15 mg) every 4 weeks while the body adapts.
  • Combined with diet and physical activity — tirzepatide complements, not replaces, lifestyle change.

  • Severe abdominal pain radiating to the back (possible pancreatitis) — stop and seek urgent care.
  • Gallbladder problems — sudden right-upper abdominal pain, jaundice, fever.
  • Severe dehydration from prolonged vomiting / diarrhoea, risk of acute kidney injury.
  • Sudden vision changes in patients with diabetic retinopathy.
  • Severe allergic reaction.

WHEN TO CALL THE DOCTOR

Call us through the in-app chat if you notice…

  • Severe or persistent vomiting, dehydration, or inability to eat for more than 48h.
  • New, severe abdominal pain that doesn't ease — A&E first.
  • Pregnancy or a positive pregnancy test — stop the medicine immediately.
  • A new medication or condition since your last consultation.

OFFICIAL SOURCE

This summary is condensed from the regulator's full product leaflet for ease of reading. The complete document — every interaction, dose adjustment and reporting note — is one click away.

EMA — Mounjaro product information

This page summarises information from the regulator-approved leaflet for reference only. It is not medical advice and does not replace the assessment of an EU-licensed doctor. Your doctor will review your individual history, dose and interactions during your consultation.

← Back to consultationYou can print this page for your records.

HI-DOCTOR NEWSLETTER

We'll tell you when we add new treatments.

At most 2 emails a month. No spam. Updates on online health, EU telemedicine, and clinical guides signed by licensed doctors.