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MEDICATION SAFETY

Alprostadil safety summary

  • INN
  • alprostadil
  • prostaglandin E1 vasodilator
  • 3 mg/g topical cream
  • brand: Vitaros

Alprostadil cream is a topical treatment for erectile dysfunction: applied to the tip of the penis, it relaxes the local blood vessels directly so blood can flow in. Because it works locally rather than through the whole body, it is an option when PDE5 tablets are unsuitable or not tolerated — most of its side effects are local too.

Erectile dysfunction in adult men, as a local alternative to tablets.

  • Apply the single-use dose to the opening at the tip of the penis 5–30 minutes before sex, following the leaflet's technique.
  • The effect lasts around 1–2 hours.
  • Maximum one dose per 24 hours, and no more than 2–3 doses per week.
  • Wash hands after applying.

Rare, but each needs prompt action.

  • An erection lasting more than 4 hours (priapism) — go to emergency care.
  • Severe or persistent penile pain, or a new curvature, lump or hardening of the penis.
  • Fainting or marked dizziness — the medicine can lower blood pressure in some men.
  • A severe local or allergic reaction (spreading rash, swelling, difficulty breathing).

WHEN TO CALL THE DOCTOR

Call us through the in-app chat if you notice…

  • An erection lasting more than 4 hours — go to emergency care first.
  • Penile pain that persists between uses, or any new lump or curvature.
  • Fainting or marked dizziness after applying.
  • Irritation in your partner that doesn't settle — the dose or method can be reviewed.

OFFICIAL SOURCE

This summary is condensed from the regulator's full product leaflet for ease of reading. The complete document — every interaction, dose adjustment and reporting note — is one click away.

AEMPS CIMA — Alprostadil 3 mg/g

This page summarises information from the regulator-approved leaflet for reference only. It is not medical advice and does not replace the assessment of an EU-licensed doctor. Your doctor will review your individual history, dose and interactions during your consultation.

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